Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN34_RS09305 Genome accession   NZ_CP068803
Coordinates   1945015..1945671 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C018404     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1940015..1950671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN34_RS09275 (JNN34_09275) dcyD 1940895..1941881 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JNN34_RS09280 (JNN34_09280) tcyL 1941896..1942564 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN34_RS09285 (JNN34_09285) tcyN 1942561..1943313 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN34_RS09290 (JNN34_09290) sdiA 1943543..1944265 (+) 723 WP_087760829.1 transcriptional regulator SdiA -
  JNN34_RS09295 (JNN34_09295) yecF 1944332..1944556 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN34_RS09300 (JNN34_09300) yecU 1944543..1944719 (-) 177 WP_001307856.1 protein YecU -
  JNN34_RS23810 - 1944802..1944873 (-) 72 Protein_1832 transcriptional regulator -
  JNN34_RS09305 (JNN34_09305) letA 1945015..1945671 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN34_RS09310 (JNN34_09310) uvrC 1945668..1947500 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  JNN34_RS09315 (JNN34_09315) pgsA 1947557..1948105 (+) 549 WP_074500281.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN34_RS09335 (JNN34_09335) yecA 1948755..1949420 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=461599 JNN34_RS09305 WP_000611328.1 1945015..1945671(+) (letA) [Escherichia coli strain RIVM_C018404]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=461599 JNN34_RS09305 WP_000611328.1 1945015..1945671(+) (letA) [Escherichia coli strain RIVM_C018404]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482