Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN40_RS01275 Genome accession   NZ_CP068802
Coordinates   248723..249379 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C018249     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 243723..254379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN40_RS01245 (JNN40_01245) dcyD 244603..245589 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JNN40_RS01250 (JNN40_01250) tcyL 245604..246272 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN40_RS01255 (JNN40_01255) tcyN 246269..247021 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN40_RS01260 (JNN40_01260) sdiA 247251..247973 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  JNN40_RS01265 (JNN40_01265) yecF 248040..248264 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN40_RS01270 (JNN40_01270) yecU 248251..248427 (-) 177 WP_000590347.1 protein YecU -
  JNN40_RS24150 - 248510..248581 (-) 72 Protein_253 transcriptional regulator -
  JNN40_RS01275 (JNN40_01275) letA 248723..249379 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN40_RS01280 (JNN40_01280) uvrC 249376..251208 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JNN40_RS01285 (JNN40_01285) pgsA 251265..251813 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN40_RS01305 (JNN40_01305) yecA 252463..253128 (+) 666 WP_000847874.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=461485 JNN40_RS01275 WP_000611328.1 248723..249379(+) (letA) [Escherichia coli strain RIVM_C018249]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=461485 JNN40_RS01275 WP_000611328.1 248723..249379(+) (letA) [Escherichia coli strain RIVM_C018249]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCACGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482