Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JM964_RS07630 Genome accession   NZ_CP068708
Coordinates   1557265..1557906 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain ID33329     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1552265..1562906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM964_RS07605 (JM964_07605) comFA/cflA 1552419..1553711 (-) 1293 WP_044668890.1 DEAD/DEAH box helicase Machinery gene
  JM964_RS07610 (JM964_07610) - 1553768..1554400 (+) 633 WP_015646510.1 YigZ family protein -
  JM964_RS07615 (JM964_07615) cysK 1554490..1555416 (+) 927 WP_044668892.1 cysteine synthase A -
  JM964_RS07620 (JM964_07620) - 1555442..1555813 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  JM964_RS07625 (JM964_07625) - 1555815..1557215 (-) 1401 WP_044668895.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  JM964_RS07630 (JM964_07630) vraR 1557265..1557906 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  JM964_RS07635 (JM964_07635) - 1557878..1558894 (-) 1017 WP_044668898.1 sensor histidine kinase -
  JM964_RS07640 (JM964_07640) liaF 1558891..1559550 (-) 660 WP_228475102.1 cell wall-active antibiotics response protein LiaF -
  JM964_RS10425 - 1559873..1560145 (-) 273 WP_408549039.1 PASTA domain-containing protein -
  JM964_RS07645 (JM964_07645) pknB 1560209..1561867 (-) 1659 Protein_1470 Stk1 family PASTA domain-containing Ser/Thr kinase -
  JM964_RS07650 (JM964_07650) - 1561867..1562604 (-) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=460906 JM964_RS07630 WP_002937025.1 1557265..1557906(-) (vraR) [Streptococcus suis strain ID33329]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=460906 JM964_RS07630 WP_002937025.1 1557265..1557906(-) (vraR) [Streptococcus suis strain ID33329]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTCCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTGGAGGTTAAGCCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACTTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413