Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JJW04_RS15920 Genome accession   NZ_CP068281
Coordinates   3245749..3246405 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CY706     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3240749..3251405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJW04_RS15890 (JJW04_15800) yecA 3242000..3242665 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  JJW04_RS15910 (JJW04_15820) pgsA 3243315..3243863 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JJW04_RS15915 (JJW04_15825) uvrC 3243920..3245752 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JJW04_RS15920 (JJW04_15830) letA 3245749..3246405 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JJW04_RS23385 - 3246547..3246618 (+) 72 Protein_3132 transcriptional regulator -
  JJW04_RS15925 (JJW04_15835) yecU 3246701..3246877 (+) 177 WP_000590347.1 protein YecU -
  JJW04_RS15930 (JJW04_15840) yecF 3246864..3247088 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JJW04_RS15935 (JJW04_15845) sdiA 3247156..3247878 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  JJW04_RS15940 (JJW04_15850) tcyN 3248108..3248860 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JJW04_RS15945 (JJW04_15855) tcyL 3248857..3249525 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JJW04_RS15950 (JJW04_15860) dcyD 3249540..3250526 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=459522 JJW04_RS15920 WP_000611335.1 3245749..3246405(-) (letA) [Escherichia coli strain CY706]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=459522 JJW04_RS15920 WP_000611335.1 3245749..3246405(-) (letA) [Escherichia coli strain CY706]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486