Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I6J12_RS08090 Genome accession   NZ_CP068060
Coordinates   1709198..1710022 (-) Length   274 a.a.
NCBI ID   WP_003037768.1    Uniprot ID   I0SA10
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1704198..1715022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS08075 (I6J12_08075) - 1705204..1705854 (-) 651 WP_003037759.1 DUF6287 domain-containing protein -
  I6J12_RS08080 (I6J12_08080) - 1705996..1706535 (-) 540 WP_003037787.1 SH3 domain-containing protein -
  I6J12_RS08085 (I6J12_08085) - 1706675..1708789 (-) 2115 WP_003037735.1 GBS Bsp-like repeat-containing protein -
  I6J12_RS08090 (I6J12_08090) comD/blpH 1709198..1710022 (-) 825 WP_003037768.1 sensor histidine kinase Regulator
  I6J12_RS08095 (I6J12_08095) - 1710142..1711077 (-) 936 WP_020999450.1 IS30 family transposase -
  I6J12_RS08100 (I6J12_08100) - 1711154..1711564 (-) 411 WP_003038906.1 hypothetical protein -
  I6J12_RS08105 (I6J12_08105) comE/blpR 1711586..1712326 (-) 741 WP_003038927.1 response regulator transcription factor Regulator
  I6J12_RS08110 (I6J12_08110) - 1712458..1713096 (-) 639 WP_003038917.1 SGNH/GDSL hydrolase family protein -
  I6J12_RS08115 (I6J12_08115) - 1713096..1713926 (-) 831 WP_003038886.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 31491.23 Da        Isoelectric Point: 4.8780

>NTDB_id=458826 I6J12_RS08090 WP_003037768.1 1709198..1710022(-) (comD/blpH) [Streptococcus anginosus strain FDAARGOS_1155]
MIVYFILLQILLIFEDVINSAIFYRQYLIGIYTILFLIMLIYINTTFKDRLEEEIIYQKNRQLEDLANYNRQIESLYNEL
RNFRHDYINILSSIKTGIDNRDIDIISSVYNSVLSKTTEQFQNPKYNITNLIKVKNEAVKSILSAKLLEAQSKGINISVE
AEKDFSESQMELLDFVTILSILMDNAIEGAQLAQSSEITVALFNSGNTNVLIIENTTDVAKIDTSDIFLCGFSSKGKDRG
IGLYNVANILKKYPNVSIITQSKDFHFRQTIEMR

Nucleotide


Download         Length: 825 bp        

>NTDB_id=458826 I6J12_RS08090 WP_003037768.1 1709198..1710022(-) (comD/blpH) [Streptococcus anginosus strain FDAARGOS_1155]
ATGATTGTATATTTTATTCTTTTGCAAATATTGTTAATTTTTGAAGATGTTATCAATTCTGCGATTTTTTATCGACAATA
TTTAATTGGTATTTATACTATTTTGTTTTTAATAATGTTGATTTATATAAATACAACTTTTAAAGATAGATTAGAGGAGG
AGATTATTTATCAAAAGAATAGGCAATTAGAAGATTTAGCAAATTATAATCGACAAATAGAATCGCTTTATAATGAACTA
AGGAATTTTCGGCATGACTATATAAATATTTTAAGTAGTATAAAAACAGGGATTGATAATCGCGATATTGATATTATATC
TAGCGTCTATAATTCAGTCTTGTCAAAAACCACGGAGCAGTTTCAAAATCCAAAATATAATATTACCAATTTAATAAAAG
TAAAAAATGAAGCAGTTAAAAGCATTTTATCCGCAAAGTTACTTGAAGCACAAAGTAAAGGAATAAACATTAGCGTTGAA
GCAGAAAAAGATTTCAGTGAGTCACAAATGGAATTGTTGGATTTTGTTACAATTCTCTCAATATTAATGGACAATGCCAT
TGAAGGAGCTCAGTTAGCACAGAGTTCGGAAATAACGGTAGCTCTTTTTAATAGTGGTAATACAAATGTCTTGATTATAG
AAAATACTACGGATGTTGCAAAGATTGATACATCAGATATCTTTTTATGTGGTTTTTCTTCAAAAGGCAAAGATCGGGGA
ATTGGTTTATATAATGTAGCAAATATATTGAAAAAATATCCTAATGTATCCATTATTACGCAAAGCAAGGATTTTCATTT
TAGACAGACAATTGAAATGAGATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(170-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SA10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

44.28

98.905

0.438
  comD/comD2 Streptococcus equinus JB1

35.87

100

0.361