Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6J12_RS06345 Genome accession   NZ_CP068060
Coordinates   1346133..1347932 (-) Length   599 a.a.
NCBI ID   WP_003035989.1    Uniprot ID   I0SDZ4
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1341133..1352932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS06320 (I6J12_06320) pepV 1341205..1342605 (-) 1401 WP_003035938.1 dipeptidase PepV -
  I6J12_RS06325 (I6J12_06325) - 1342625..1343230 (-) 606 WP_003036081.1 nitroreductase family protein -
  I6J12_RS06330 (I6J12_06330) - 1343335..1343970 (-) 636 WP_003036196.1 AAA family ATPase -
  I6J12_RS06335 (I6J12_06335) - 1344199..1345065 (-) 867 WP_003036064.1 hypothetical protein -
  I6J12_RS06340 (I6J12_06340) - 1345062..1346069 (-) 1008 WP_003036079.1 hypothetical protein -
  I6J12_RS06345 (I6J12_06345) uvrC 1346133..1347932 (-) 1800 WP_003035989.1 excinuclease ABC subunit UvrC Machinery gene
  I6J12_RS06350 (I6J12_06350) ptsP 1348083..1349816 (-) 1734 WP_003036105.1 phosphoenolpyruvate--protein phosphotransferase -
  I6J12_RS06355 (I6J12_06355) - 1349818..1350081 (-) 264 WP_003023815.1 phosphocarrier protein HPr -
  I6J12_RS06360 (I6J12_06360) nrdH 1350479..1350697 (+) 219 WP_003023812.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 599 a.a.        Molecular weight: 68947.38 Da        Isoelectric Point: 9.4757

>NTDB_id=458806 I6J12_RS06345 WP_003035989.1 1346133..1347932(-) (uvrC) [Streptococcus anginosus strain FDAARGOS_1155]
MNNLIQSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIEDFEFIVTESNIEALLLEIN
LIKENQPKYNIMLKDDKSYPFIKITNEKYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTICHNEQHFFQNMAQEVADFLKGHDNKIIDELKGKMTSAAEKMEFEKAAEYRDLLQSIATLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQNKSHLVPNEILIPSDIDEESVRAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGRLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVVGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNIAKDVIQNQLGLDIPIAGLQ
KNDKHQTHELLFGDPLKVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGLKRKQNLMRHFKSL
TNIKKASVDEIVEVGVPRKVAEAVQRKLNPAESQAELKD

Nucleotide


Download         Length: 1800 bp        

>NTDB_id=458806 I6J12_RS06345 WP_003035989.1 1346133..1347932(-) (uvrC) [Streptococcus anginosus strain FDAARGOS_1155]
ATGAATAACTTGATTCAATCAAAATTAGAATTGCTGCCGACTAGTCCCGGTTGCTATATTCATAAAGATAAAAATGGTAC
CATTATTTACGTAGGTAAGGCTAAGAATTTGCGCAATCGGGTGCGCTCTTATTTTCGTGGGAGTCATGATACTAAGACTG
AAGCGCTGGTGTCTGAGATTGAGGATTTTGAGTTTATTGTCACGGAGTCTAATATTGAAGCCCTGTTGCTTGAAATCAAT
CTGATTAAGGAAAATCAGCCTAAGTACAACATCATGCTCAAGGATGATAAGTCCTACCCTTTTATCAAAATTACCAATGA
GAAATATCCACGTCTAATTATTACGCGTCAGGTCAAGAAAGACGGTGGCTTGTATTTTGGTCCTTATCCTGATGTAGGTG
CTGCCAATGAAATTAAGCGTCTGCTGGATCGAATTTTCCCTTTTCGCAAGTGTACCAATCCGCCTGAGAAGGTTTGTTTC
TACTACCACATCGGACAGTGCCGAGCTCACACTATTTGCCATAATGAGCAGCATTTTTTTCAAAATATGGCTCAGGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAATACCGAGATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATGGCGAAG
GATTTGCAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGCGTACAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGACGTGAATATGTTTCCTTATTACAATGATCCCGATGAGGATTTTCTGACCTATATTGGTCAAT
TTTATCAGAATAAATCTCATCTGGTGCCCAATGAAATTTTGATTCCGTCTGATATTGATGAGGAATCAGTACGGGCTGTG
GTGGATACAAAAATTCTTAAGCCTCAACGAGGAGAAAAGAAACAGCTGGTCAATCTAGCAATTAAGAATGCTCAAGTTAG
TTTACAGCAGAAGTTTGACTTATTAGAGAAATCTGTTGAAAAAACGCAAGGAGCAATTGAAAATCTAGGCCGGCTCCTCA
ATATTCCCACTCCAGTTCGGATTGAGTCGTTTGATAATTCCAATATTATGGGAACTAGTCCTGTTTCAGCTATGGTGGTT
TTTATCAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTGTCGGTCCTGATGACTATGCTAG
TATGCGAGAAGTGATTAAGCGCCGTTACAGTCGGGTTATGCGAGATGGTTTAATACCGCCTGATCTTATTGTCATTGATG
GTGGTCAGGGGCAAGTCAATATTGCTAAAGACGTTATTCAAAATCAATTAGGGTTAGATATTCCTATCGCTGGTTTGCAA
AAGAACGACAAGCACCAGACGCATGAATTACTCTTTGGCGATCCTTTGAAAGTAGTTGAGTTATCTCGCAATTCGCAGGA
ATTTTTCCTCCTCCAACGTATTCAGGATGAAGTTCACCGCTTTGCCATTACCTTCCATCGCCAGCTTCGCTCAAAAAACT
CCTTTTCATCGCAATTGGATGGTATTGAGGGGCTAGGACTCAAGCGCAAGCAAAATCTGATGCGACACTTTAAATCATTG
ACCAACATCAAAAAAGCCAGCGTGGATGAAATTGTCGAAGTGGGTGTCCCGAGAAAAGTAGCGGAGGCTGTGCAGAGAAA
ACTCAATCCTGCAGAATCTCAGGCAGAGTTAAAAGACTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SDZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

90

98.497

0.886
  uvrC Streptococcus pneumoniae R6

90

98.497

0.886
  uvrC Streptococcus pneumoniae D39

90

98.497

0.886