Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6J12_RS00985 Genome accession   NZ_CP068060
Coordinates   199756..200388 (+) Length   210 a.a.
NCBI ID   WP_003036430.1    Uniprot ID   I0SDI7
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 194756..205388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS00965 (I6J12_00965) - 195192..195932 (+) 741 WP_003036337.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6J12_RS00970 (I6J12_00970) stkP 195929..197803 (+) 1875 WP_003036358.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6J12_RS00975 (I6J12_00975) liaF 198064..198762 (+) 699 WP_003036398.1 cell wall-active antibiotics response protein LiaF -
  I6J12_RS00980 (I6J12_00980) - 198759..199754 (+) 996 WP_003036415.1 sensor histidine kinase -
  I6J12_RS00985 (I6J12_00985) vraR 199756..200388 (+) 633 WP_003036430.1 response regulator transcription factor Regulator
  I6J12_RS00990 (I6J12_00990) - 200428..201828 (+) 1401 WP_003036370.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6J12_RS00995 (I6J12_00995) - 201830..202204 (+) 375 WP_020999484.1 S1 RNA-binding domain-containing protein -
  I6J12_RS01000 (I6J12_01000) - 202330..202647 (-) 318 WP_003036352.1 DUF960 domain-containing protein -
  I6J12_RS01005 (I6J12_01005) - 202767..203300 (-) 534 WP_003031472.1 DUF402 domain-containing protein -
  I6J12_RS01010 (I6J12_01010) recX 203387..204163 (-) 777 WP_003036445.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23698.31 Da        Isoelectric Point: 4.9093

>NTDB_id=458764 I6J12_RS00985 WP_003036430.1 199756..200388(+) (vraR) [Streptococcus anginosus strain FDAARGOS_1155]
MHILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVEKALELRPDVIMMDIVMPEMSGIKATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=458764 I6J12_RS00985 WP_003036430.1 199756..200388(+) (vraR) [Streptococcus anginosus strain FDAARGOS_1155]
ATGCATATTTTATTAGTAGATGACCATGAAATGGTACGACTTGGCTTGAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAAAGCTTTGGAGTTGCGCCCAGATGTGATTATGATGGACA
TTGTTATGCCTGAAATGAGTGGGATTAAAGCGACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGACGCAGGTGCTAAAGGATATATGCTGAAAACATCTAGTGC
TGATGATATTTTACGAGCTGTCCGAAAAGTAGCTAAGGGTGAACTTGCCATTGAAACAGAGGTCAGCCAAAAAGTGGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SDI7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41