Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6J14_RS08555 Genome accession   NZ_CP068057
Coordinates   1688322..1690304 (+) Length   660 a.a.
NCBI ID   WP_115253272.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1683322..1695304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS08550 (I6J14_08550) - 1683811..1687038 (-) 3228 WP_115276474.1 serum opacification factor -
  I6J14_RS08555 (I6J14_08555) hexB 1688322..1690304 (+) 1983 WP_115253272.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6J14_RS08560 (I6J14_08560) - 1690315..1691535 (+) 1221 WP_115253194.1 MFS transporter -
  I6J14_RS08565 (I6J14_08565) ruvA 1691537..1692130 (+) 594 WP_115253193.1 Holliday junction branch migration protein RuvA Machinery gene
  I6J14_RS08570 (I6J14_08570) - 1692140..1692712 (+) 573 WP_115253192.1 DNA-3-methyladenine glycosylase I -
  I6J14_RS08575 (I6J14_08575) - 1692715..1693068 (+) 354 WP_115253191.1 VOC family protein -
  I6J14_RS08580 (I6J14_08580) cinA 1693192..1694463 (+) 1272 WP_115253190.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74589.03 Da        Isoelectric Point: 5.5847

>NTDB_id=458712 I6J14_RS08555 WP_115253272.1 1688322..1690304(+) (hexB) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MSKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSSEDLPLSLRRHATSK
IKNQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAAYGSLLIATGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEIAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIPISSADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQKNDFFVKESDVSEKLPESNFHDTEIDKTVKDQR
TEQFPDLGENTRFSSVKRASRSQDEVTDADHPGFDLKNKQKLSQMLTRLENEERSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=458712 I6J14_RS08555 WP_115253272.1 1688322..1690304(+) (hexB) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATATCAAAAATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCATCTGAAGATCTCCCTTTGAGCTTGCGGCGACATGCGACCAGTAAA
ATCAAAAATCAGAGTGATCTCTTTCGAATTAGAACGCTTGGTTTTAGGGGAGAAGCTTTACCATCGGTTGCTTCTATCAG
CAAAATTACGATAAAAACAGCTACTAAGGAAGCTGCTTATGGCTCTCTACTAATTGCAACTGGTGGAGAGATTGAAACGC
TTGAGGAAACCTCGACGCCTGTAGGTACCAAGATTAAGGTTGAAAACCTTTTTTATAATACACCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCTCATATTGTTGATGTGGTTAATCGTTTGAGTTTGGCTCATCCAGAAATTGCTTT
CACCCTGATTAGTGATGGCCGTCAATTAACTCAGACGTCAGGGACGGGAGATCTTCGGCAGGCTATTGCGGGCATTTATG
GCTTGAATACTGCGAAGAAAATGATTCCTATTTCCAGTGCTGATTTGGACTTTGAAGTGTCTGGCTATGTCAGTTTACCA
GAGTTGACACGCGCTAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTATGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAAGAATGATTTTTTTGTCA
AAGAATCAGACGTTTCTGAAAAACTGCCTGAGAGTAATTTTCATGATACAGAGATTGACAAGACTGTAAAGGATCAAAGA
ACGGAGCAGTTTCCTGATTTAGGAGAGAATACAAGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGGTAAC
TGATGCTGATCACCCTGGATTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
GATCGGTATTTCCTGAATTGGATTATTTTGGTCAGATGCACGGCACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAAGTTGACAGTAGTTT
ACAGCAATTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAATTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGCATCTTTCTGGAAGTGTATGGGCACAATACTTTCATCTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTATCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTGC
TGCAATTGGCGCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAAGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAACTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.127

100

0.683