Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6J14_RS01935 Genome accession   NZ_CP068057
Coordinates   399866..401650 (+) Length   594 a.a.
NCBI ID   WP_115252921.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 394866..406650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS01895 (I6J14_01895) - 394973..395230 (-) 258 WP_003051110.1 thioredoxin family protein -
  I6J14_RS01900 (I6J14_01900) - 395240..396236 (-) 997 Protein_374 permease -
  I6J14_RS01905 (I6J14_01905) - 396298..396618 (-) 321 WP_003051109.1 metalloregulator ArsR/SmtB family transcription factor -
  I6J14_RS01910 (I6J14_01910) - 396788..397495 (+) 708 WP_003051107.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6J14_RS01915 (I6J14_01915) - 397573..398949 (+) 1377 WP_003051105.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  I6J14_RS11115 - 399032..399804 (+) 773 Protein_378 Cof-type HAD-IIB family hydrolase -
  I6J14_RS01935 (I6J14_01935) uvrC 399866..401650 (+) 1785 WP_115252921.1 excinuclease ABC subunit UvrC Machinery gene
  I6J14_RS10820 - 401704..401871 (-) 168 WP_236593279.1 hypothetical protein -
  I6J14_RS10825 - 401861..402016 (-) 156 WP_003051090.1 thiamine pyrophosphate-dependent enzyme -
  I6J14_RS01945 (I6J14_01945) - 402390..402992 (+) 603 WP_003051089.1 nitroreductase family protein -
  I6J14_RS01950 (I6J14_01950) pepV 403170..404579 (+) 1410 WP_003051087.1 dipeptidase PepV -
  I6J14_RS01955 (I6J14_01955) - 405343..406017 (+) 675 WP_115252920.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68095.75 Da        Isoelectric Point: 9.4128

>NTDB_id=458652 I6J14_RS01935 WP_115252921.1 399866..401650(+) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVHKVCF
YYHLGQCCAHTICHTDKAYWDGLVEDVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGHLLGIDKPVRIEAFDNSNIQGTSPVAAMVV
FLDGKPNKKDYRKFKIKTVVGQDDYASMREVIFRRYSRVKHEGLVAPDLIIIDGGLGQVNAAREVIEDRLGLTIPIAGLQ
KNDKHQTHELLFGKPLEVVPLPRNSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQILLKHFKTM
TAIAAASPDEIHSLGIPRAVASAVHQHLTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=458652 I6J14_RS01935 WP_115252921.1 399866..401650(+) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGAATGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGCCCTGGTTGCTACTTGCATAAGGACAAAGAGGGAAC
CATTATCTATGTAGGCAAGGCTAAGAATTTGAAGAACCGAGTGCGGTCTTATTTTCGTGGTAGCCATGATACCAAGACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTCACCGAATCAAATACTGAAGCCCTCTTGCTTGAAATCAAC
TTGATTCAAGAGAACATGCCCAAATATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GACCTTTCCTCGCCTGCTCATTACGAGACAGATTAAGAAAAATGACGGCCTATATTTCGGACCCTATCCAGATTCGTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGTATTTTCCCTTTTAAGAAATGTAAAAACCCTGTCCATAAGGTTTGTTTT
TATTACCATTTAGGACAGTGTTGTGCTCATACCATCTGCCATACAGATAAGGCTTATTGGGATGGTCTGGTAGAGGATGT
CAAACACTTTTTGAATGGCAAGGATGATAAGATTATTGATGGGCTGCGGGCAAAAATGTTAGCAGCTTCTGAGGAAATGG
CATTTGAACGTGCTGCTGAATATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACTAAGCAGCGGGTGATGAGTAAG
GACTTGCAAGACAGGGATATTTTTGGCTACTTTGTTGATAAGGGATGGATGTGTGTCCAAGTTTTCTTTGTACGTCAAGG
GAAATTAATCCAGCGGGATGTCAACCTCTTTCCTTACTACAACGACGCGGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTATCAAGATAAACAGCATTTCATCCCCAAAGAAGTCTTTATTCCAGAAGCTATTGATGAAGAACTAGTAGCCGCTATT
GTGCCAACAAAAATCATCAAACCAAAACGAGGTGAGAAAAAACAATTGGTGGCTTTGGCGACCAAGAACGCACGCGTTAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCCATTGACAATCTAGGCCACTTGTTAG
GGATTGACAAGCCAGTCCGTATTGAGGCTTTTGATAATTCCAATATTCAAGGGACAAGCCCTGTAGCGGCTATGGTTGTT
TTTCTTGACGGGAAACCTAATAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGCCAAGATGATTATGCCAG
CATGAGGGAAGTGATTTTTCGAAGGTATAGCCGTGTTAAACATGAAGGACTGGTAGCTCCTGATTTAATCATCATTGATG
GTGGGCTAGGGCAAGTCAATGCGGCCAGAGAAGTGATTGAAGACCGACTAGGATTAACTATTCCTATTGCGGGCCTGCAA
AAAAATGATAAGCACCAGACCCATGAATTGCTCTTTGGCAAGCCACTCGAGGTAGTCCCCTTACCCCGTAATTCAGAAGA
ATTTTTCCTCTTGCATCGCATCCAAGATGAGGTGCACCGCTTTGCGATTACTTTCCACCGACAGGTTCGCAGTAAAAATT
CATTCTCTTCGAAATTGGATAAGATTCCAGGACTAGGTCCGAAGCGCAAGCAGATACTGCTTAAACATTTTAAAACCATG
ACAGCCATTGCGGCAGCTAGTCCAGATGAGATTCATTCTTTAGGGATTCCTAGAGCGGTGGCATCAGCTGTCCATCAGCA
TCTGACAGACAGTCAGCAAAGTTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.552

99.158

0.749
  uvrC Streptococcus pneumoniae R6

75.212

99.158

0.746
  uvrC Streptococcus pneumoniae D39

75.212

99.158

0.746