Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6J15_RS00945 Genome accession   NZ_CP068056
Coordinates   188403..189047 (-) Length   214 a.a.
NCBI ID   WP_020916314.1    Uniprot ID   A0AB33AKG7
Organism   Streptococcus lutetiensis strain FDAARGOS_1158     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 183403..194047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J15_RS00920 (I6J15_00920) comFA/cflA 183416..184714 (-) 1299 WP_020916319.1 DEAD/DEAH box helicase Machinery gene
  I6J15_RS00925 (I6J15_00925) - 184769..185395 (+) 627 WP_111712652.1 YigZ family protein -
  I6J15_RS00930 (I6J15_00930) cysK 185495..186424 (+) 930 WP_020916317.1 cysteine synthase A -
  I6J15_RS00935 (I6J15_00935) - 186523..186879 (-) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  I6J15_RS09300 (I6J15_00940) - 186879..188279 (-) 1401 WP_081048448.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6J15_RS00945 (I6J15_00945) vraR 188403..189047 (-) 645 WP_020916314.1 response regulator Regulator
  I6J15_RS00950 (I6J15_00950) - 189031..190056 (-) 1026 WP_020916313.1 sensor histidine kinase -
  I6J15_RS00955 (I6J15_00955) liaF 190053..190748 (-) 696 WP_058813684.1 cell wall-active antibiotics response protein LiaF -
  I6J15_RS00960 (I6J15_00960) stkP/pknB 190849..192762 (-) 1914 WP_058813683.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6J15_RS00965 (I6J15_00965) - 192762..193499 (-) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24009.84 Da        Isoelectric Point: 5.0404

>NTDB_id=458542 I6J15_RS00945 WP_020916314.1 188403..189047(-) (vraR) [Streptococcus lutetiensis strain FDAARGOS_1158]
MAQKIRVILVDDHEMVRLGLKSFFNLQPDVEVIGEAGNGIDGIKLALDLKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDQRPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDED

Nucleotide


Download         Length: 645 bp        

>NTDB_id=458542 I6J15_RS00945 WP_020916314.1 188403..189047(-) (vraR) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGGCCCAGAAAATTAGAGTTATCCTAGTTGATGATCATGAAATGGTGCGTCTTGGTTTGAAAAGTTTTTTTAACTTGCA
ACCAGATGTTGAAGTTATTGGCGAAGCAGGAAATGGAATTGACGGAATTAAACTTGCTTTAGACTTAAAACCAGATGTCG
TAGTGATGGATTTGGTGATGCCTGAAATGAGTGGTGTTGAAGCGACCTTAAAACTCTTAAAAGAGTGGAAAGAAGCTAAA
ATCCTTGTTCTGACATCTTATCTTGATAATGAAAAAATCTATCCAGTTATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGTGCCGCTGAAATTCTTAACGCTATTCAGAAAGTAGCACGTGGTGAACTAGCAATCGAAACAGAAGTCGATA
AGAAAATCAAAGCACACGATCAAAGACCTGAATTGCATGAGGATTTGACAGCGCGTGAGCGAGATATTTTAAGACTTTTA
GCCAAAGGTTATGATAATCAGACTATTGCTGATGAACTGTTTATTTCGTTAAAAACCGTTAAAACACACGTTTCAAATAT
CTTGGCTAAGCTAGAAGTGGATGACCGTACACAAGCGGTTGTCTATGCCTTTAAGCATCATTTAGTACCGCAAGATGAGG
ATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33AKG7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.054

100

0.388