Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C663_RS19815 Genome accession   NC_020244
Coordinates   3991920..3993122 (-) Length   400 a.a.
NCBI ID   WP_015385166.1    Uniprot ID   -
Organism   Bacillus subtilis XF-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3986920..3998122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C663_RS19795 (C663_3950) rocE 3987034..3988437 (-) 1404 WP_041518155.1 amino acid permease -
  C663_RS19800 (C663_3951) rocD 3988660..3989865 (-) 1206 WP_041518158.1 ornithine aminotransferase -
  C663_RS19805 (C663_3952) rocR 3990106..3991491 (+) 1386 WP_015385164.1 arginine utilization regulatory protein RocR -
  C663_RS19810 (C663_3953) - 3991473..3991658 (-) 186 Protein_3997 ATP-binding protein -
  C663_RS21485 - 3991774..3991900 (-) 127 Protein_3998 hypothetical protein -
  C663_RS19815 (C663_3954) htrA 3991920..3993122 (-) 1203 WP_015385166.1 serine protease HtrC Regulator
  C663_RS19820 (C663_3955) vicX 3993204..3993998 (-) 795 WP_015483958.1 MBL fold metallo-hydrolase Regulator
  C663_RS19825 (C663_3956) walI 3994020..3994862 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C663_RS19830 (C663_3957) walH 3994849..3996216 (-) 1368 WP_041518280.1 WalRK two-component regulatory system regulator WalH -
  C663_RS19835 (C663_3958) walK 3996206..3998041 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42766.53 Da        Isoelectric Point: 5.3354

>NTDB_id=45844 C663_RS19815 WP_015385166.1 3991920..3993122(-) (htrA) [Bacillus subtilis XF-1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKPDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=45844 C663_RS19815 WP_015385166.1 3991920..3993122(-) (htrA) [Bacillus subtilis XF-1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTATCTTTCAAATGAAGGGCTGGATACGGGCG
CTTTAGATCAGCAGCAGAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAACCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAATCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(182-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

42.228

96.5

0.408
  htrA Streptococcus pneumoniae TIGR4

44.242

82.5

0.365
  htrA Streptococcus pneumoniae D39

44.242

82.5

0.365
  htrA Streptococcus pneumoniae Rx1

44.242

82.5

0.365
  htrA Streptococcus pneumoniae R6

44.242

82.5

0.365

Multiple sequence alignment