Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JJN14_RS07740 Genome accession   NZ_CP067992
Coordinates   1537507..1539342 (-) Length   611 a.a.
NCBI ID   WP_201058336.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1532507..1544342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS07715 (JJN14_07715) - 1533958..1534245 (-) 288 WP_070478540.1 rhodanese-like domain-containing protein -
  JJN14_RS07720 (JJN14_07720) - 1534360..1534938 (-) 579 WP_201058333.1 uracil-DNA glycosylase family protein -
  JJN14_RS07725 (JJN14_07725) pepV 1534992..1536392 (-) 1401 WP_201058334.1 dipeptidase PepV -
  JJN14_RS07730 (JJN14_07730) - 1536405..1537010 (-) 606 WP_201058335.1 nitroreductase family protein -
  JJN14_RS07735 (JJN14_07735) - 1537101..1537514 (-) 414 WP_236253685.1 hypothetical protein -
  JJN14_RS07740 (JJN14_07740) uvrC 1537507..1539342 (-) 1836 WP_201058336.1 excinuclease ABC subunit UvrC Machinery gene
  JJN14_RS07745 (JJN14_07745) - 1539381..1540082 (-) 702 WP_125429430.1 M57 family metalloprotease -
  JJN14_RS07750 (JJN14_07750) - 1540145..1540924 (-) 780 WP_094753435.1 alpha/beta hydrolase -
  JJN14_RS07755 (JJN14_07755) - 1540992..1542653 (-) 1662 WP_094753434.1 ribonuclease J -

Sequence

Protein


Download         Length: 611 a.a.        Molecular weight: 70184.68 Da        Isoelectric Point: 8.5644

>NTDB_id=458248 JJN14_RS07740 WP_201058336.1 1537507..1539342(-) (uvrC) [Streptococcus mitis strain S022-V7-A3]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAAAAQTMEFERAAEYRDLIQAIGTLRIKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVEAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVVRRRYGRVQRDGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQEEEELAQVAEQGIIEWRENE

Nucleotide


Download         Length: 1836 bp        

>NTDB_id=458248 JJN14_RS07740 WP_201058336.1 1537507..1539342(-) (uvrC) [Streptococcus mitis strain S022-V7-A3]
ATGAATAACTTGATTAAATCAAAACTAGAGCTCTTACCGACCAGCCCTGGTTGCTACATTCACAAGGATAAAAACGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGAAACCGTGTGCGGTCCTATTTTCGTGGAAGTCATGATACCAAGACGG
AAGCTCTGGTGTCCGAAATTGTGGATTTTGAATTTATCGTTACTGAGTCCAATATTGAGGCACTTCTCCTAGAAATTAAT
CTGATCAAGGAAAATAAGCCTAAATACAATATCATGCTCAAGGATGACAAGTCTTATCCTTTCATCAAAATCACCAATGA
ACGCTATCCTCGTTTGATTATTACCCGACAGGTCAAGAAGGACGGAGGTCTCTACTTTGGACCTTATCCAGATGTGGGGG
CGGCCAATGAAATCAAGCGGTTGCTGGATAGGATTTTCCCTTTTCGTAAGTGTACCAATCCACCATCTAAGGTCTGTTTT
TACTATCATATCGGTCAATGTATGGCCCACACCATCTGTAAGAAGGATGAGGCCTATTTCAAGTCTATGGCTCAGGAGGT
TTCCGATTTTCTAAAAGGGCAGGATGACAAAATCATTGATGACCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AATTTGAACGTGCGGCGGAATACCGTGACCTAATTCAGGCTATTGGAACGCTTCGAATCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGGGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTCATCGAGCGAGACGTCAATCTTTTCCCTTATTACAATGATCCGGACGAGGACTTCTTAACCTATGTGGGACAAT
TCTATCAAGAAAAATCCCACCTAGTACCCAATGAAGTGCTGATTCCGCAGGATATTGATGAAGAAGCCGTCGAGGCCTTA
GTGGATACTAAGATTCTCAAACCCCAGCGTGGAGAGAAGAAACAACTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTGGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACACAAGGAGCTATTGAAAATCTAGGACGCTTGCTCC
AAATTCCGACCCCAGTCCGTATCGAATCTTTCGATAACTCCAACATCATGGGAACCAGTCCTGTTTCAGCCATGGTGGTC
TTTGTTAACGGTAAACCGAGTAAGAAGGATTACCGTAAGTACAAGATAAAAACCGTTGTTGGACCGGACGATTATGCCAG
CATGAGAGAAGTCGTTCGCAGGCGCTATGGTCGAGTACAGCGTGACGGTTTGACTCCTCCAGATTTGATTGTCATCGATG
GGGGACAAGGTCAGGTCAATATCGCCAAGCAAGTCATTCAAGAGGAGCTGGGCTTGGATATCCCCATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGAGTTGTCTCGCAATTCTCAGGA
GTTTTTCCTCCTCCAACGCATTCAAGATGAGGTCCACCGATTTGCCATTACTTTCCACCGCCAACTGCGCTCCAAAAATT
CCTTTTCATCACAACTGGATGGAATTGAAGGGCTGGGACCTAAACGCAAGCAGAATCTCATGAAGCATTTCAAGTCTCTC
ACTAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCTAGAGCGGTTGCAGAGGCTGTGCAGAGGAA
GTTGAATCCGCAGGAAGAAGAGGAATTAGCTCAAGTAGCGGAACAAGGAATAATAGAATGGAGAGAAAATGAGTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

96.689

98.854

0.956
  uvrC Streptococcus pneumoniae R6

96.358

98.854

0.953
  uvrC Streptococcus pneumoniae D39

96.358

98.854

0.953