Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JI426_RS11350 Genome accession   NZ_CP067426
Coordinates   2293610..2294266 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O22:H8 strain 154     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2288610..2299266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JI426_RS11320 (JI426_002234) dcyD 2289490..2290476 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JI426_RS11325 (JI426_002235) tcyL 2290491..2291159 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JI426_RS11330 (JI426_002236) tcyN 2291156..2291908 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JI426_RS11335 (JI426_002237) sdiA 2292138..2292860 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  JI426_RS11340 (JI426_002238) yecF 2292927..2293151 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JI426_RS11345 yecU 2293138..2293314 (-) 177 WP_000590347.1 protein YecU -
  JI426_RS28610 - 2293397..2293468 (-) 72 Protein_2232 transcriptional regulator -
  JI426_RS11350 (JI426_002239) letA 2293610..2294266 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JI426_RS11355 (JI426_002240) uvrC 2294263..2296095 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JI426_RS11360 (JI426_002241) pgsA 2296152..2296700 (+) 549 WP_096844713.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JI426_RS11380 (JI426_002245) yecA 2297350..2298015 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=458132 JI426_RS11350 WP_000611335.1 2293610..2294266(+) (letA) [Escherichia coli O22:H8 strain 154]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=458132 JI426_RS11350 WP_000611335.1 2293610..2294266(+) (letA) [Escherichia coli O22:H8 strain 154]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486