Detailed information NTG0045782

Bioinformatically predicted

Overview

• Name: pilM
• Type: Machinery gene
• Locus tag: THTHE16_RS07075
• Genome accession: NC_017272
• Coordinates: 1341033..1342166 (+)
• Length: 377 a.a.
• NCBI ID: WP_014510582.1
• Uniprot ID: F6DIG3
• Organism: Thermus thermophilus SG0.5JP17-16
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1336033..1347166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
THTHE16_RS07045 (Ththe16_1384)	-	1336744..1337109 (-)	366	WP_014510577.1	hypothetical protein	-
THTHE16_RS07060 (Ththe16_1386)	-	1337851..1339302 (+)	1452	WP_014510579.1	HD-GYP domain-containing protein	-
THTHE16_RS07065 (Ththe16_1387)	-	1339353..1339844 (+)	492	WP_041445020.1	DUF5317 family protein	-
THTHE16_RS07070 (Ththe16_1388)	-	1339899..1340903 (+)	1005	WP_014510581.1	homoisocitrate dehydrogenase	-
THTHE16_RS07075 (Ththe16_1389)	pilM	1341033..1342166 (+)	1134	WP_014510582.1	type IV pilus assembly protein PilM	Machinery gene
THTHE16_RS07080 (Ththe16_1390)	pilN	1342159..1342782 (+)	624	WP_014510583.1	competence protein	Machinery gene
THTHE16_RS07085 (Ththe16_1391)	pilO	1342772..1343353 (+)	582	WP_008632866.1	type 4a pilus biogenesis protein PilO	Machinery gene
THTHE16_RS07090 (Ththe16_1392)	pilW	1343350..1344228 (+)	879	WP_014510585.1	hypothetical protein	Machinery gene
THTHE16_RS07095 (Ththe16_1393)	pilQ	1344225..1346492 (+)	2268	WP_014510586.1	secretin N-terminal domain-containing protein	Machinery gene

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 41411.06 Da
• Isoelectric Point: 4.4148

>NTDB_id=45782 THTHE16_RS07075 WP_014510582.1 1341033..1342166(+) (pilM) [Thermus thermophilus SG0.5JP17-16]
MFKSLSQLFRPRVEALGLEIGASALKLVEVSGNPPALKALASRPTPPGLLVEGMVAEPAALAQEIKELLLEARTRKRYVV
TALSNLAVILRPIQVPKMPLKEMEEAVRWEAERYIPFPIDEVVLDFAPLTPLSEVQEGEQVQVMVAAARQEAVAGVLEAL
RGAGLVPVVLDVKPFAGLYPLEARLAEEPDRVFLVLDIGAESTSLVLLRGDKPLAVRVLTLSGKDFTEAIARSFNLDLLA
AEEVKRTYGMATLPTEDEELLLDFDAERERYSPGRIYDAIRPVLVELTQELRRSLEFFRIQLEEAPPEVGYLLGGGSKLR
GLASLLTDTLGVNFEPVNPWEAVTVDPKRFEAEKLQEMGPEFAVALGLALRGVEPFD

Nucleotide

• Length: 1134 bp

>NTDB_id=45782 THTHE16_RS07075 WP_014510582.1 1341033..1342166(+) (pilM) [Thermus thermophilus SG0.5JP17-16]
GTGTTCAAAAGCCTTAGCCAGCTCTTCCGACCCAGGGTTGAGGCCCTGGGCTTGGAGATTGGAGCCTCCGCCCTGAAGCT
TGTGGAGGTTTCCGGGAACCCGCCCGCCCTCAAAGCCCTGGCCTCCCGCCCCACCCCGCCCGGCCTCCTGGTGGAAGGGA
TGGTGGCCGAGCCCGCCGCGTTGGCCCAGGAGATCAAGGAGCTTCTCCTCGAGGCCCGCACCCGCAAGCGCTACGTGGTC
ACCGCCCTCTCCAACCTGGCGGTCATCCTCCGCCCCATCCAGGTTCCCAAGATGCCCCTCAAGGAGATGGAGGAGGCGGT
GCGCTGGGAGGCGGAGCGCTACATTCCCTTCCCCATTGACGAGGTGGTCCTGGACTTCGCCCCCCTGACCCCCCTCTCCG
AGGTGCAGGAGGGGGAGCAGGTCCAGGTGATGGTGGCGGCGGCGCGGCAGGAGGCGGTGGCGGGGGTCCTCGAGGCCCTG
AGGGGGGCGGGGCTCGTCCCCGTGGTGCTGGACGTGAAGCCCTTCGCCGGGCTTTACCCTCTGGAGGCCAGGCTCGCGGA
GGAACCCGACCGGGTCTTCCTCGTCCTGGACATCGGGGCCGAGAGCACGAGCCTCGTCCTGCTCCGGGGGGACAAGCCCC
TGGCGGTGCGCGTCCTCACCCTCTCGGGCAAGGACTTCACCGAGGCCATCGCCCGAAGCTTCAACCTGGACCTCCTCGCC
GCCGAGGAGGTGAAGCGGACCTACGGGATGGCCACCCTCCCCACCGAGGACGAGGAGCTCCTCCTGGACTTTGACGCCGA
GCGGGAGCGCTACAGCCCGGGGCGCATCTACGACGCCATCCGCCCGGTGCTGGTGGAGCTCACCCAGGAGCTCCGCCGTA
GCCTAGAGTTCTTCCGCATCCAGCTGGAAGAAGCCCCGCCCGAGGTGGGCTACCTCCTGGGCGGGGGAAGCAAGTTGAGG
GGGCTTGCCTCCCTCCTCACCGACACCCTGGGGGTGAACTTTGAGCCCGTCAACCCCTGGGAGGCGGTAACGGTGGACCC
CAAGCGCTTTGAGGCGGAGAAGCTCCAGGAAATGGGGCCCGAGTTCGCCGTAGCCCTGGGCCTGGCCCTGAGGGGGGTGG
AGCCCTTTGATTAG

Domains

Predicted by InterproScan.

• Type IV pilus assembly protein PilM; (PilM_2) (17-372)

3D structure

• AlphaFold DB: F6DIG3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilM	Thermus thermophilus HB27	97.878	100	0.979