Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JJB24_RS12270 Genome accession   NZ_CP067299
Coordinates   2528938..2529594 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ABW_A33     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2523938..2534594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJB24_RS12240 (JJB24_12235) yecA 2525190..2525855 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  JJB24_RS12260 (JJB24_12255) pgsA 2526504..2527052 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JJB24_RS12265 (JJB24_12260) uvrC 2527109..2528941 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JJB24_RS12270 (JJB24_12265) letA 2528938..2529594 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JJB24_RS24115 - 2529736..2529852 (+) 117 WP_001302039.1 hypothetical protein -
  JJB24_RS12275 (JJB24_12270) yecU 2529890..2530066 (+) 177 WP_000590344.1 protein YecU -
  JJB24_RS12280 (JJB24_12275) yecF 2530053..2530277 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JJB24_RS12285 (JJB24_12280) sdiA 2530345..2531067 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  JJB24_RS12290 (JJB24_12285) tcyN 2531297..2532049 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JJB24_RS12295 (JJB24_12290) tcyL 2532046..2532714 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JJB24_RS12300 (JJB24_12295) dcyD 2532729..2533715 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=457639 JJB24_RS12270 WP_000611328.1 2528938..2529594(-) (letA) [Escherichia coli strain ABW_A33]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=457639 JJB24_RS12270 WP_000611328.1 2528938..2529594(-) (letA) [Escherichia coli strain ABW_A33]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482