NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	JHX98_RS09150	Genome accession	NZ_CP067010
Coordinates	1815423..1816019 (-)	Length	198 a.a.
NCBI ID	WP_011185063.1	Uniprot ID	A2RGV1
Organism	Streptococcus pyogenes strain iGAS376
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1810423..1821019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JHX98_RS09115 (JHX98_09115)	-	1810484..1810789 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
JHX98_RS09120 (JHX98_09120)	ruvX	1810801..1811220 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
JHX98_RS09125 (JHX98_09125)	-	1811217..1811486 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
JHX98_RS09130 (JHX98_09130)	spx	1811599..1811997 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
JHX98_RS09135 (JHX98_09135)	recA	1812288..1813424 (-)	1137	WP_002982186.1	recombinase RecA	Machinery gene
JHX98_RS09140 (JHX98_09140)	cinA	1813513..1814784 (-)	1272	WP_011018313.1	competence/damage-inducible protein A	Machinery gene
JHX98_RS09145 (JHX98_09145)	-	1814853..1815413 (-)	561	WP_010922755.1	DNA-3-methyladenine glycosylase I	-
JHX98_RS09150 (JHX98_09150)	ruvA	1815423..1816019 (-)	597	WP_011185063.1	Holliday junction branch migration protein RuvA	Machinery gene
JHX98_RS09155 (JHX98_09155)	-	1816021..1817241 (-)	1221	WP_023077191.1	MFS transporter	-
JHX98_RS09160 (JHX98_09160)	hexB	1817252..1819234 (-)	1983	WP_011889221.1	DNA mismatch repair endonuclease MutL	Machinery gene
JHX98_RS09165 (JHX98_09165)	-	1819329..1820346 (-)	1018	Protein_1759	site-specific integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21852.19 Da Isoelectric Point: 6.4948

                                >NTDB_id=457017 JHX98_RS09150 WP_011185063.1 1815423..1816019(-) (ruvA) [Streptococcus pyogenes strain iGAS376]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=457017 JHX98_RS09150 WP_011185063.1 1815423..1816019(-) (ruvA) [Streptococcus pyogenes strain iGAS376]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG

AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGCATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae R6	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae D39	66.497	99.495	0.662
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.394	100	0.414

Detailed information NTG0457017