Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JH656_RS10770 Genome accession   NZ_CP066839
Coordinates   2209785..2210441 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Ec-RL2-1X     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2204785..2215441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JH656_RS10740 (JH656_10645) dcyD 2205664..2206650 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JH656_RS10745 (JH656_10650) tcyL 2206665..2207333 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JH656_RS10750 (JH656_10655) tcyN 2207330..2208082 (+) 753 WP_089567384.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JH656_RS10755 (JH656_10660) sdiA 2208312..2209034 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  JH656_RS10760 (JH656_10665) yecF 2209102..2209326 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JH656_RS10765 (JH656_10670) yecU 2209313..2209489 (-) 177 WP_000590344.1 protein YecU -
  JH656_RS24660 - 2209527..2209643 (-) 117 WP_001302039.1 hypothetical protein -
  JH656_RS10770 (JH656_10675) letA 2209785..2210441 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JH656_RS10775 (JH656_10680) uvrC 2210438..2212270 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  JH656_RS10780 (JH656_10685) pgsA 2212327..2212875 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JH656_RS10800 (JH656_10705) yecA 2213524..2214189 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=456622 JH656_RS10770 WP_000611328.1 2209785..2210441(+) (letA) [Escherichia coli strain Ec-RL2-1X]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=456622 JH656_RS10770 WP_000611328.1 2209785..2210441(+) (letA) [Escherichia coli strain Ec-RL2-1X]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482