Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HUW56_RS18540 Genome accession   NZ_CP055160
Coordinates   3787382..3788038 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain WLYS23     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3782382..3793038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUW56_RS18510 (HUW56_18510) oppF 3782912..3783829 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HUW56_RS18515 (HUW56_18515) - 3783936..3785123 (+) 1188 WP_079891125.1 putative glycoside hydrolase -
  HUW56_RS18520 (HUW56_18520) - 3785241..3785819 (+) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  HUW56_RS18525 (HUW56_18525) spx 3785998..3786393 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HUW56_RS18530 (HUW56_18530) - 3786450..3787106 (-) 657 WP_032874459.1 TerC family protein -
  HUW56_RS18535 (HUW56_18535) - 3787289..3787399 (+) 111 Protein_3624 adaptor protein MecA -
  HUW56_RS18540 (HUW56_18540) mecA 3787382..3788038 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HUW56_RS18545 (HUW56_18545) - 3788189..3789349 (+) 1161 WP_032874460.1 competence protein CoiA family protein -
  HUW56_RS18550 (HUW56_18550) pepF 3789577..3791406 (+) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  HUW56_RS18555 (HUW56_18555) - 3791444..3791611 (-) 168 WP_032874462.1 hypothetical protein -
  HUW56_RS18560 (HUW56_18560) spxH 3791897..3792799 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=456549 HUW56_RS18540 WP_003155032.1 3787382..3788038(+) (mecA) [Bacillus velezensis strain WLYS23]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=456549 HUW56_RS18540 WP_003155032.1 3787382..3788038(+) (mecA) [Bacillus velezensis strain WLYS23]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895