Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JGU77_RS14080 Genome accession   NZ_CP066806
Coordinates   2935260..2935916 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain TCM3e1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2930260..2940916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGU77_RS14050 (JGU77_14050) yecA 2931511..2932176 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  JGU77_RS14070 (JGU77_14070) pgsA 2932826..2933374 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JGU77_RS14075 (JGU77_14075) uvrC 2933431..2935263 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JGU77_RS14080 (JGU77_14080) letA 2935260..2935916 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JGU77_RS14085 (JGU77_14085) yecU 2936211..2936387 (+) 177 WP_032245964.1 protein YecU -
  JGU77_RS14090 (JGU77_14090) yecF 2936374..2936598 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JGU77_RS14095 (JGU77_14095) sdiA 2936665..2937387 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  JGU77_RS14100 (JGU77_14100) tcyN 2937617..2938369 (-) 753 WP_063624912.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JGU77_RS14105 (JGU77_14105) tcyL 2938366..2939034 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JGU77_RS14110 (JGU77_14110) dcyD 2939049..2940035 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=456449 JGU77_RS14080 WP_000611328.1 2935260..2935916(-) (letA) [Escherichia coli strain TCM3e1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=456449 JGU77_RS14080 WP_000611328.1 2935260..2935916(-) (letA) [Escherichia coli strain TCM3e1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482