Detailed information NTG0456444

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: HUW35_RS10305
• Genome accession: NZ_CP055157
• Coordinates: 2511243..2512667 (-)
• Length: 474 a.a.
• NCBI ID: WP_181252270.1
• Uniprot ID: A0A7H8PYM4
• Organism: Microbulbifer sp. YPW1
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 2506243..2517667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUW35_RS10290 (HUW35_10295)	-	2506800..2507291 (+)	492	WP_181252267.1	PilX N-terminal domain-containing pilus assembly protein	-
HUW35_RS10295 (HUW35_10300)	-	2507313..2510759 (+)	3447	WP_181252268.1	pilus assembly protein	-
HUW35_RS10300 (HUW35_10305)	-	2510772..2511191 (+)	420	WP_181252269.1	type IV pilin protein	-
HUW35_RS10305 (HUW35_10310)	pilR	2511243..2512667 (-)	1425	WP_181252270.1	sigma-54 dependent transcriptional regulator	Regulator
HUW35_RS10310 (HUW35_10315)	-	2512696..2514348 (-)	1653	WP_255463226.1	nitrogen regulation protein NR(II)	-
HUW35_RS10315 (HUW35_10320)	-	2514475..2516103 (+)	1629	WP_181252271.1	NAD+ synthase	-
HUW35_RS10320 (HUW35_10325)	-	2516208..2517137 (-)	930	WP_181252272.1	outer membrane protein assembly factor BamD	-

Sequence

Protein

• Length: 474 a.a.
• Molecular weight: 52955.60 Da
• Isoelectric Point: 5.7503

>NTDB_id=456444 HUW35_RS10305 WP_181252270.1 2511243..2512667(-) (pilR) [Microbulbifer sp. YPW1]
MADRQPIALIIDDEPDICNLISMTLHRMNVRSDIAMSVAEARRQLEKKRYDFCLTDMKLPDGTGLQVVEHIQDLPADRLL
PVAVITAHGNMDTAIAALKLGAFDFVSKPVNLERLRNLVQLALRLNEARYVEQQEFPTLLQGQSPAIQELRKQIEKVARS
DAPALIFGEAGSGKELTARCIHQHGPRAQQPFVPVYCASLAAERLEETLFGSESEPGLIQRAHGGTLFLDEVASLPPDIQ
VKLLRAIQEKRYFSEIDAARTDLDIRILSASKQPLAKAVREGRFRSDLYYCINVIELHAPPLRKRLEDIPLLVRDMLRRI
STAKKGAAPKAAPDAISALQAYPLPGNLRELENILERAVTLSERNTLHAADLLIPAMQPTRPPETGEPSAYSNNNELEQP
VMTSLPESKQSTYPGQFATSDYSSLDDFLQTIEREAIETTLNETDWNRTAAAEKLGISFRSLRYRLKKLGLENE

Nucleotide

• Length: 1425 bp

>NTDB_id=456444 HUW35_RS10305 WP_181252270.1 2511243..2512667(-) (pilR) [Microbulbifer sp. YPW1]
ATGGCCGATCGTCAACCCATAGCACTAATAATCGACGACGAACCGGATATCTGTAACTTGATATCCATGACCCTACACCG
CATGAACGTGCGCTCAGATATCGCCATGTCAGTCGCCGAAGCCCGTCGACAATTGGAAAAAAAGCGCTACGACTTCTGCC
TGACCGACATGAAGTTACCGGATGGTACTGGGCTGCAGGTTGTTGAACATATTCAGGATCTACCGGCAGACCGTTTACTT
CCGGTTGCCGTCATAACCGCGCACGGCAATATGGATACCGCCATTGCCGCGCTTAAACTCGGTGCATTTGATTTTGTCAG
CAAGCCGGTGAATCTAGAGCGTCTGCGCAACCTGGTGCAGCTGGCGTTGCGCTTGAACGAAGCCCGCTACGTGGAGCAGC
AGGAATTCCCGACACTGCTACAGGGGCAATCTCCAGCAATACAGGAACTGCGCAAGCAAATTGAAAAAGTTGCGCGCAGC
GATGCTCCGGCGCTTATCTTCGGCGAGGCGGGCAGTGGTAAAGAACTGACTGCACGCTGTATCCACCAACACGGCCCGCG
CGCGCAGCAACCATTTGTACCCGTTTACTGTGCCAGCCTGGCCGCAGAGCGGCTCGAAGAGACGCTATTTGGCAGCGAAT
CGGAACCGGGTTTAATCCAGCGTGCACATGGCGGCACTCTGTTTCTCGATGAAGTTGCCAGCCTTCCCCCGGATATTCAG
GTCAAACTCCTTCGAGCCATTCAGGAGAAACGTTATTTTTCAGAAATAGATGCAGCACGCACCGACCTGGATATTCGCAT
CCTCAGCGCCAGCAAACAGCCCCTGGCTAAAGCAGTGCGAGAGGGACGATTTCGCAGCGATCTTTACTACTGTATCAACG
TTATTGAACTACACGCTCCACCCCTTCGAAAAAGGCTTGAGGATATTCCGCTTCTGGTTCGCGATATGCTACGCAGGATT
TCCACCGCAAAAAAAGGCGCTGCTCCGAAGGCCGCACCAGATGCCATCAGCGCCCTACAGGCCTACCCCCTCCCTGGAAA
CCTGCGCGAGCTTGAGAACATACTCGAGCGCGCCGTGACCTTGAGTGAGCGCAACACACTGCATGCCGCAGACCTGCTGA
TTCCAGCTATGCAGCCGACCAGGCCTCCCGAAACTGGAGAGCCGTCAGCTTATTCAAATAACAACGAACTCGAACAGCCA
GTGATGACGTCACTTCCGGAGTCAAAGCAATCCACCTACCCCGGCCAGTTCGCAACTTCAGATTACTCAAGCCTGGATGA
CTTTCTGCAAACCATCGAGCGGGAAGCTATCGAAACGACCCTCAATGAAACCGACTGGAACAGGACGGCAGCAGCAGAAA
AACTGGGGATCAGTTTCCGTTCCCTGCGCTACCGTTTGAAAAAGCTGGGGTTGGAAAACGAATGA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (141-297)

• Response regulator receiver domain (Response_reg) (9-119)

• Bacterial regulatory protein, Fis family (HTH_8) (429-469)

3D structure

• AlphaFold DB: A0A7H8PYM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	47.899	100	0.481
pilR	Acinetobacter baumannii strain A118	42.623	100	0.439