Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   JEK78_RS09110 Genome accession   NZ_CP066801
Coordinates   2210950..2212074 (+) Length   374 a.a.
NCBI ID   WP_200263591.1    Uniprot ID   -
Organism   Streptomyces sp. HSG2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2205950..2217074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JEK78_RS09095 - 2206760..2207524 (+) 765 Protein_1800 hypothetical protein -
  JEK78_RS09100 - 2207521..2209233 (-) 1713 WP_242483316.1 hypothetical protein -
  JEK78_RS09105 radA 2209463..2210872 (+) 1410 WP_200263590.1 DNA repair protein RadA Machinery gene
  JEK78_RS09110 disA 2210950..2212074 (+) 1125 WP_200263591.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  JEK78_RS09115 - 2212174..2212968 (-) 795 WP_200263592.1 hypothetical protein -
  JEK78_RS09120 - 2213335..2214312 (+) 978 WP_200263593.1 A/G-specific adenine glycosylase -
  JEK78_RS09125 - 2214506..2215045 (+) 540 WP_200263594.1 SigE family RNA polymerase sigma factor -
  JEK78_RS09130 - 2215093..2215704 (+) 612 WP_200264065.1 hypothetical protein -
  JEK78_RS09135 cseB 2215808..2216512 (+) 705 WP_200263595.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40170.95 Da        Isoelectric Point: 5.0162

>NTDB_id=456376 JEK78_RS09110 WP_200263591.1 2210950..2212074(+) (disA) [Streptomyces sp. HSG2]
MAANDRAAAPGKSAASAGSEGLMRATLSAVAPGTALRDGLERVLRGNTGGLILLGSDRTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSADLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRFDEVAGTLSALEIEDLVTVRDLSSVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALAELDKLSHAELLELNTVARALGYAGSPESLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVEGVGETRARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=456376 JEK78_RS09110 WP_200263591.1 2210950..2212074(+) (disA) [Streptomyces sp. HSG2]
GTGGCAGCCAACGACCGGGCAGCGGCTCCCGGCAAGTCCGCAGCGAGTGCCGGCTCCGAGGGTCTGATGCGCGCCACGTT
GAGCGCGGTGGCGCCCGGCACGGCGCTCCGGGACGGGCTGGAGCGGGTGCTGCGCGGCAACACCGGCGGCCTGATCCTGC
TCGGTTCCGACCGGACGGTGGAGGCCATGTGCACCGGCGGATTCGTCCTCGACGTCGAGTTCACCGCGACCCGGTTGAGG
GAGCTGTGCAAGCTCGACGGTGGCATCGTGCTCTCGGCGGACCTTTCCAAGATCCTTCGCGCGGGTGTCCAGCTCGTCCC
GGACCCGACGATCCCGACGGAGGAGACCGGCACCCGCCATCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTGTCGGTCTCGCAGTCGATGCGTCTGATCGCCCTCTACGTCGACGGGCAGCGGCGCGTCCTGGAGGACTCCGCGGCG
ATCCTGTCCCGAGCCAATCAGGCGCTGGCCACCCTGGAGCGCTACAAACTGCGTTTCGACGAGGTCGCCGGGACCCTCTC
CGCCCTGGAGATCGAGGACCTCGTCACCGTCCGTGATCTGTCCTCGGTCGCCCAGCGGTTGGAGATGGTGCGGCGGATCG
CGACCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGGCTGCTGGCCCTGCAGCTGGACGAGCTGATCGCC
GGCGTGGAGCCGGAGCGCGAGCTGGTGGTCCGCGACTACGTGCCGGAGCCGACGGCGAAGCGGTCCCGGACGGTGGAGGA
GGCGCTGGCCGAGTTGGACAAGCTCTCCCACGCCGAGCTGCTGGAACTGAACACGGTGGCGCGCGCCCTGGGGTACGCGG
GGTCGCCGGAGTCGCTGGACTCGGCCGTGTCGCCGCGCGGTTTTCGACTGCTGGCCAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGTTGGTGGAGCACTTCGGGGGCTTGCAGAAGCTGTTGGCCGCCAGCGTCGACGACCTCCAGGCCGTGGA
GGGGGTCGGCGAGACCCGGGCCCGCAGTGTGCGCGAGGGGTTGTCCCGGCTCGCGGAGTCCTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.706

96.524

0.441