Detailed information NTG0455201

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: JF649_RS07295
• Genome accession: NZ_CP066541
• Coordinates: 1463539..1466367 (-)
• Length: 942 a.a.
• NCBI ID: WP_129322388.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS270
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1458539..1471367

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JF649_RS07265 (JF649_07250)	-	1459215..1460180 (+)	966	WP_002988504.1	LacI family DNA-binding transcriptional regulator	-
JF649_RS07270 (JF649_07255)	nusB	1460321..1460773 (-)	453	WP_012560925.1	transcription antitermination factor NusB	-
JF649_RS07275 (JF649_07260)	-	1460766..1461155 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
JF649_RS07280 (JF649_07265)	efp	1461201..1461758 (-)	558	WP_002988496.1	elongation factor P	-
JF649_RS07285 (JF649_07270)	-	1461854..1462315 (-)	462	WP_076639277.1	deaminase	-
JF649_RS07290 (JF649_07275)	-	1462350..1463423 (-)	1074	WP_129321681.1	Xaa-Pro peptidase family protein	-
JF649_RS07295 (JF649_07280)	uvrA	1463539..1466367 (-)	2829	WP_129322388.1	excinuclease ABC subunit UvrA	Machinery gene
JF649_RS07300 (JF649_07285)	-	1466570..1467514 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
JF649_RS07305 (JF649_07290)	-	1467646..1468302 (+)	657	WP_010922629.1	DUF1129 domain-containing protein	-
JF649_RS07310 (JF649_07295)	rpsR	1468435..1468674 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
JF649_RS07315 (JF649_07300)	ssb	1468839..1469330 (-)	492	WP_248848135.1	single-stranded DNA-binding protein	Machinery gene
JF649_RS07320 (JF649_07305)	rpsF	1469352..1469642 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
JF649_RS07325 (JF649_07310)	-	1469815..1470108 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104124.34 Da
• Isoelectric Point: 6.0690

>NTDB_id=455201 JF649_RS07295 WP_129322388.1 1463539..1466367(-) (uvrA) [Streptococcus pyogenes strain MGAS270]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDSIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLFGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=455201 JF649_RS07295 WP_129322388.1 1463539..1466367(-) (uvrA) [Streptococcus pyogenes strain MGAS270]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAATCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATAGTA
TTCGTAGCCGTTTGTTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTCCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAAAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGGGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGCTACATG
AATGAATTGACTTGTGCTACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACCT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCATCAAAGAGACAATGACCGTTTGATCGAGAGCCTGA
AAAAAATGCGTGATTTGGGTAATACGTTAATTGTGGTAGAACACGATGAAGATACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTTTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.607	100	0.846
uvrA	Streptococcus pneumoniae TIGR4	84.607	100	0.846
uvrA	Streptococcus pneumoniae D39	84.607	100	0.846