Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IGS65_RS02110 Genome accession   NZ_CP066294
Coordinates   414207..415994 (+) Length   595 a.a.
NCBI ID   WP_002282457.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 409207..420994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS02085 (IGS65_002085) - 409292..409933 (+) 642 WP_002265582.1 DUF4352 domain-containing protein -
  IGS65_RS02090 (IGS65_002090) eno 410328..411626 (+) 1299 WP_002270049.1 surface-displayed alpha-enolase -
  IGS65_RS09805 (IGS65_002095) - 411820..411984 (+) 165 WP_002277707.1 hypothetical protein -
  IGS65_RS02100 (IGS65_002100) - 412196..412891 (+) 696 WP_002264091.1 YjjG family noncanonical pyrimidine nucleotidase -
  IGS65_RS02105 (IGS65_002105) - 412935..414089 (-) 1155 WP_002271054.1 low temperature requirement protein A -
  IGS65_RS02110 (IGS65_002110) uvrC 414207..415994 (+) 1788 WP_002282457.1 excinuclease ABC subunit UvrC Machinery gene
  IGS65_RS02115 (IGS65_002115) - 416141..416743 (+) 603 WP_192072268.1 nitroreductase family protein -
  IGS65_RS02120 (IGS65_002120) pepV 416758..418164 (+) 1407 WP_014677952.1 dipeptidase PepV -
  IGS65_RS02125 (IGS65_002125) - 418237..418824 (+) 588 WP_002264094.1 uracil-DNA glycosylase family protein -
  IGS65_RS02130 (IGS65_002130) - 418952..419254 (-) 303 WP_002304943.1 helix-turn-helix domain-containing protein -
  IGS65_RS02135 (IGS65_002135) - 419346..419696 (+) 351 WP_192072267.1 nuclear transport factor 2 family protein -
  IGS65_RS02140 (IGS65_002140) - 419714..420517 (+) 804 WP_002271050.1 amidohydrolase family protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68907.30 Da        Isoelectric Point: 9.3836

>NTDB_id=454554 IGS65_RS02110 WP_002282457.1 414207..415994(+) (uvrC) [Streptococcus mutans strain 27-3]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRDIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARISLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLNGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLREEREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=454554 IGS65_RS02110 WP_002282457.1 414207..415994(+) (uvrC) [Streptococcus mutans strain 27-3]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGCAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTGGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGTATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAATCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAGATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTATTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGTTGAACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAAGAGAG
CTTGCGAGAGGAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.728

99.664

0.765
  uvrC Streptococcus pneumoniae R6

76.391

99.664

0.761
  uvrC Streptococcus pneumoniae D39

76.391

99.664

0.761