Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I2453_RS06655 Genome accession   NZ_CP066242
Coordinates   1270878..1271543 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain RM1221     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1265878..1276543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2453_RS06640 groES 1267734..1267994 (+) 261 WP_002825273.1 co-chaperone GroES -
  I2453_RS06645 groL 1268015..1269652 (+) 1638 WP_002860445.1 chaperonin GroEL -
  I2453_RS06650 dccS 1269695..1270885 (-) 1191 WP_002855957.1 two-component system sensor histidine kinase DccS -
  I2453_RS06655 ciaR 1270878..1271543 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  I2453_RS06660 - 1271691..1272290 (+) 600 WP_002855731.1 bacteriohemerythrin -
  I2453_RS06665 - 1272301..1272549 (+) 249 WP_002853192.1 ribbon-helix-helix domain-containing protein -
  I2453_RS06675 - 1272807..1274054 (-) 1248 WP_002853241.1 ArsS family sensor histidine kinase -
  I2453_RS06680 - 1274051..1274725 (-) 675 WP_002853196.1 response regulator transcription factor -
  I2453_RS06685 htrA 1274801..1276219 (-) 1419 WP_002860448.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=454403 I2453_RS06655 WP_002853205.1 1270878..1271543(-) (ciaR) [Campylobacter jejuni strain RM1221]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=454403 I2453_RS06655 WP_002853205.1 1270878..1271543(-) (ciaR) [Campylobacter jejuni strain RM1221]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGAGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTGCTTAAAAATAAAAACAACTTTTTAAGTACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362