Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   A7A1_RS13390 Genome accession   NC_019896
Coordinates   2632218..2634317 (+) Length   699 a.a.
NCBI ID   WP_015252215.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis str. BSP1     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2627218..2639317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A1_RS13360 (A7A1_1520) ykvN 2627249..2627605 (+) 357 WP_003245808.1 winged helix-turn-helix transcriptional regulator -
  A7A1_RS13365 (A7A1_1519) queF 2628155..2628652 (-) 498 WP_003218613.1 preQ(1) synthase -
  A7A1_RS13370 (A7A1_1518) queE 2628670..2629401 (-) 732 WP_015252213.1 7-carboxy-7-deazaguanine synthase QueE -
  A7A1_RS13375 (A7A1_1517) queD 2629394..2629843 (-) 450 WP_003232462.1 6-carboxytetrahydropterin synthase QueD -
  A7A1_RS13380 (A7A1_1516) queC 2629836..2630495 (-) 660 WP_003245417.1 7-cyano-7-deazaguanine synthase QueC -
  A7A1_RS13385 (A7A1_1515) - 2630809..2631852 (-) 1044 WP_015252214.1 hypothetical protein -
  A7A1_RS13390 (A7A1_1514) clpE 2632218..2634317 (+) 2100 WP_015252215.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  A7A1_RS13395 (A7A1_1513) motA 2634704..2635516 (+) 813 WP_003238984.1 flagellar motor stator protein MotA -
  A7A1_RS13400 (A7A1_1512) motB 2635488..2636273 (+) 786 WP_003232473.1 flagellar motor protein MotB -
  A7A1_RS13405 (A7A1_1511) mhqR 2636313..2636750 (-) 438 WP_003232475.1 MarR family transcriptional regulator MhqR -
  A7A1_RS13410 (A7A1_1510) kinD 2636943..2638463 (+) 1521 WP_015252216.1 sporulation kinase KinD -
  A7A1_RS13415 (A7A1_1509) - 2638490..2638921 (-) 432 WP_003245685.1 hypothetical protein -
  A7A1_RS13420 (A7A1_1508) spo0E 2639007..2639264 (-) 258 WP_003218598.1 aspartyl-phosphate phosphatase Spo0E -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77921.07 Da        Isoelectric Point: 5.2425

>NTDB_id=45440 A7A1_RS13390 WP_015252215.1 2632218..2634317(+) (clpE) [Bacillus subtilis subsp. subtilis str. BSP1]
MRCQHCHQNEATIRLNMQINSVHKQMVLCETCYNELTRKPSMSMGSQSFGFPFEQAFQPKEKSAAKQSGKKGLLDELAQN
ITNGAKAGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVA
NTGIRGQFEERMKQLITELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAAL
ERRFQPVMVQEPSIEQAILILQGIKDKYEAYHGVTFSDEAIKACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLLIDELN
DEDAAERLTAIEAEKTKALEEENYELAAKLRDEELALEKKLNSSSAHTAVTVEAEHIQEIIEQKTGIPVGKLQADEQTKM
KELEAKLHERVIGQEAAVQKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKTLADELFGTKDAIIRLDMSEYME
KHAISKIIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGAGEKQTKVGFQSDDSVIEEQTLIDSLSMFFKPEFLNRFDSIIEFRSLEKEHLVKIVSLLLGELEETLAERGIRLNVTD
EAKEKIAELGYHPSFGARPLRRTIQEWVEDEMTDLLLDNGEITSFHVILEDDKIKVRAK

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=45440 A7A1_RS13390 WP_015252215.1 2632218..2634317(+) (clpE) [Bacillus subtilis subsp. subtilis str. BSP1]
ATGCGTTGTCAACATTGTCATCAAAACGAGGCGACGATTCGCCTTAACATGCAAATAAATTCCGTTCATAAACAGATGGT
TCTTTGTGAAACTTGCTATAACGAACTGACCCGTAAACCTTCAATGAGTATGGGTTCTCAATCTTTCGGATTTCCGTTTG
AACAGGCATTCCAGCCGAAAGAAAAGAGCGCAGCAAAACAAAGCGGAAAAAAAGGGCTGCTTGATGAGCTGGCTCAAAAT
ATTACAAACGGTGCTAAAGCCGGTCTCATTGATCCCGTCATCGGCCGTGATGATGAAGTGGCGCGAGTGATCGAAATTCT
AAACCGCCGCAACAAAAACAATCCGGTTCTTATTGGTGAGCCGGGTGTGGGGAAAACTGCCATCGCTGAAGGGCTCGCTT
TAAAAATTGCTGAAGGTGATGTTCCAAACAAACTGAAAAACAAAGAGCTATATTTGCTTGATGTTGCATCCCTTGTTGCA
AATACAGGGATCAGAGGCCAATTTGAGGAGAGAATGAAACAGCTGATCACTGAGCTGAAGGAACGAAAAAATGTCATTCT
GTTCATTGATGAAATTCACCTTCTCGTCGGCGCAGGCTCTGCAGAAGGATCAATGGACGCCGGCAACATTCTCAAACCGG
CCCTAGCCAGAGGCGAACTGCAAGTCATTGGCGCGACAACACTGAAAGAATATCGTCAAATCGAAAAAGATGCCGCGCTG
GAAAGACGTTTTCAGCCTGTCATGGTGCAGGAGCCTTCAATTGAACAGGCTATCCTCATTCTGCAAGGGATTAAAGACAA
ATACGAGGCGTACCATGGCGTAACATTCAGTGATGAAGCAATCAAAGCGTGTGTCACTTTATCATCCCGCTACATTCAGG
ACAGACACCTGCCGGATAAAGCAATTGATTTATTAGATGAAGCAGGTTCAAAAGCCAACCTGTTAATTGATGAACTGAAT
GATGAGGATGCCGCTGAACGCTTAACTGCAATTGAAGCCGAAAAAACAAAAGCCCTGGAAGAAGAAAATTACGAACTGGC
GGCAAAACTCCGTGATGAAGAACTCGCATTGGAGAAAAAACTGAACAGCTCCTCCGCTCATACCGCTGTCACTGTGGAAG
CTGAGCACATTCAGGAAATTATTGAACAAAAAACAGGCATCCCTGTCGGCAAACTGCAGGCAGACGAACAAACGAAAATG
AAAGAGCTTGAAGCAAAACTTCATGAACGCGTGATCGGACAAGAAGCCGCTGTTCAAAAAGTGGCAAAGGCGGTAAGACG
AAGCCGCGCCGGATTAAAATCCAAAAACAGACCAGTCGGCTCCTTCCTCTTCGTAGGTCCTACCGGCGTAGGGAAAACAG
AGCTTTCTAAAACACTGGCAGATGAATTATTCGGCACAAAAGACGCTATTATCCGACTCGATATGAGCGAATACATGGAG
AAACACGCCATATCTAAAATTATCGGTTCACCGCCTGGATATGTCGGCCATGAGGAAGCTGGACAATTAACTGAGAAAGT
GCGCCGCAATCCTTACAGCATTGTGTTGCTGGATGAGATTGAAAAAGCACACCCAGACGTTCAGCATATGTTCCTGCAAA
TTATGGAAGATGGCCGTCTGACAGACAGCCAAGGCAGAACTGTAAGCTTCAAAGACACAGTGATCATCATGACAAGTAAT
GCGGGTGCTGGTGAGAAACAAACGAAAGTCGGTTTCCAATCAGATGACAGTGTCATCGAAGAACAAACATTAATTGATTC
ACTGAGCATGTTCTTTAAACCTGAGTTCCTCAACCGTTTTGACAGCATTATTGAGTTCCGCTCATTGGAAAAAGAACATC
TTGTCAAAATCGTCAGCCTTCTTCTTGGAGAACTTGAAGAAACATTGGCGGAACGGGGCATTCGCTTGAATGTGACAGAT
GAAGCGAAAGAAAAAATTGCTGAGCTGGGCTACCACCCTTCATTCGGTGCACGTCCGCTTAGAAGAACCATTCAAGAATG
GGTTGAGGATGAAATGACCGATCTGCTGCTTGATAATGGCGAGATCACAAGTTTTCACGTGATTTTAGAAGATGATAAAA
TCAAAGTGCGAGCGAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(253-352)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-247)

AAA domain (Cdc48 subfamily) (AAA_2)

(437-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(609-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

55.855

100

0.594
  clpC Lactococcus lactis subsp. cremoris KW2

56.011

100

0.587
  clpE Streptococcus pneumoniae TIGR4

55.062

100

0.568
  clpE Streptococcus pneumoniae Rx1

55.062

100

0.568
  clpE Streptococcus pneumoniae D39

55.062

100

0.568
  clpE Streptococcus pneumoniae R6

55.062

100

0.568
  clpC Bacillus subtilis subsp. subtilis str. 168

53.701

90.844

0.488
  clpC Streptococcus pneumoniae Rx1

45.732

93.848

0.429
  clpC Streptococcus pneumoniae D39

45.732

93.848

0.429
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.847

89.7

0.429
  clpC Streptococcus thermophilus LMD-9

45.427

93.848

0.426
  clpC Streptococcus thermophilus LMG 18311

44.97

93.848

0.422
  clpC Streptococcus pneumoniae TIGR4

46.299

90.844

0.421
  clpC Streptococcus mutans UA159

46.216

88.841

0.411
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

42.244

86.695

0.366

Multiple sequence alignment