Detailed information NTG0045423

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: I33_RS12340
• Genome accession: NC_017195
• Coordinates: 2485171..2487501 (-)
• Length: 776 a.a.
• NCBI ID: WP_041519416.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. subtilis str. RO-NN-1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2480171..2492501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I33_RS12310 (I33_2636)	yqxA	2480510..2480848 (-)	339	WP_014477382.1	YqxA family protein	-
I33_RS12315 (I33_2637)	spoIIP	2480865..2482070 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
I33_RS12320 (I33_2638)	gpr	2482133..2483239 (-)	1107	WP_014477384.1	GPR endopeptidase	-
I33_RS12325 (I33_2639)	rpsT	2483443..2483709 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
I33_RS12330 (I33_2640)	holA	2483724..2484767 (-)	1044	WP_014477385.1	DNA polymerase III subunit delta	-
I33_RS20990 (I33_2641)	-	2484807..2484956 (-)	150	WP_003229985.1	hypothetical protein	-
I33_RS20480	yqzM	2484997..2485131 (+)	135	WP_003229983.1	YqzM family protein	-
I33_RS12340 (I33_2643)	comEC	2485171..2487501 (-)	2331	WP_041519416.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I33_RS12345 (I33_2645)	comEB	2487505..2488074 (-)	570	WP_014477387.1	ComE operon protein 2	-
I33_RS12350 (I33_2646)	comEA	2488141..2488758 (-)	618	WP_014477388.1	competence protein ComEA	Machinery gene
I33_RS12355 (I33_2647)	comER	2488842..2489663 (+)	822	WP_014477389.1	late competence protein ComER	-
I33_RS12360 (I33_2648)	yqeM	2489729..2490472 (-)	744	WP_014477390.1	class I SAM-dependent methyltransferase	-
I33_RS12365 (I33_2649)	rsfS	2490469..2490825 (-)	357	WP_014477391.1	ribosome silencing factor	-
I33_RS12370 (I33_2650)	yqeK	2490843..2491403 (-)	561	WP_014477392.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
I33_RS12375 (I33_2651)	nadD	2491393..2491962 (-)	570	WP_014477393.1	nicotinate-nucleotide adenylyltransferase	-
I33_RS12380 (I33_2652)	yhbY	2491974..2492264 (-)	291	WP_014477394.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86706.39 Da
• Isoelectric Point: 7.3798

>NTDB_id=45423 I33_RS12340 WP_041519416.1 2485171..2487501(-) (comEC) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIMLIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDREKWAAAYRIQSADEKEQLLYIEPGMSCELTGTLEEPKHATVPGAFGYNEYLYRQHI
HWNFSVKSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLAVVHLLAISGLHV
GILTAALFYIMIHLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLFFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTLCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITKIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVLVLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPQQRGHVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNMKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=45423 I33_RS12340 WP_041519416.1 2485171..2487501(-) (comEC) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
ATGCGTAATTCGCGCTTATTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATGTTAATCAAAACGAGGCACGCTTTTCTCATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATCCCAAAAATTGACGGCGACCGTATGTCAATGATGGTTAAGACACCTGATAGGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGACGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACCTTGGAAGAACCGAAACACGCAACTGTGCCGGGTGCATTTGGTTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTTCTCTGTCAAGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGCCGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGCTTTGTTTTATATCATGATTCACCTTGGTATCACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGTTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGTTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTATGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGTTAATCACAAAAATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTCTGCTCT
TTTTATTCACAGTCACAATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGCGGC
ATTTGCTGCACGGTGCTGGTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTCGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCAGCAGCGGGGTCATGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCCTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTTGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGAACGTGTTTCCAAATATGAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATTCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (19-170)

• Competence protein (Competence) (208-469)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	96.649	100	0.966