Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H73_RS05915 Genome accession   NZ_CP066073
Coordinates   1159707..1161491 (-) Length   594 a.a.
NCBI ID   WP_003054314.1    Uniprot ID   A0ABU0A8H6
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1154707..1166491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS05890 (I6H73_05890) pepV 1155494..1156903 (-) 1410 WP_003054303.1 dipeptidase PepV -
  I6H73_RS05895 (I6H73_05895) - 1157081..1157683 (-) 603 WP_003054310.1 nitroreductase family protein -
  I6H73_RS11580 - 1157996..1159654 (+) 1659 Protein_1165 thiamine pyrophosphate-dependent enzyme -
  I6H73_RS05915 (I6H73_05915) uvrC 1159707..1161491 (-) 1785 WP_003054314.1 excinuclease ABC subunit UvrC Machinery gene
  I6H73_RS05920 (I6H73_05920) - 1161621..1161770 (-) 150 WP_003054304.1 hypothetical protein -
  I6H73_RS05925 (I6H73_05925) - 1161826..1163202 (-) 1377 WP_003054296.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  I6H73_RS05930 (I6H73_05930) - 1163280..1163987 (-) 708 WP_003054308.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6H73_RS05935 (I6H73_05935) - 1164035..1164706 (-) 672 WP_015017085.1 DUF1524 domain-containing protein -
  I6H73_RS05940 (I6H73_05940) - 1164924..1165490 (-) 567 WP_003058443.1 sugar O-acetyltransferase -
  I6H73_RS05945 (I6H73_05945) - 1165506..1166180 (-) 675 WP_003058422.1 HAD family phosphatase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68052.72 Da        Isoelectric Point: 9.3251

>NTDB_id=453660 I6H73_RS05915 WP_003054314.1 1159707..1161491(-) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVNKVCF
YYHLGQCCAHTICHTDKAYWDGLVEDVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIAIMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNEAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPQRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGYLLGIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVIFRRYSRVKHEGLVAPDLIIIDGGLGQVNAAREVIEDRLGLTIPIAGLQ
KNDKHQTHELLFGKPLEVVPLPRNSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQILLKHFKTM
TAIAAASPDEIHSLGIPRAVASAVHQHLTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=453660 I6H73_RS05915 WP_003054314.1 1159707..1161491(-) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGAATGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGTCCTGGTTGCTACTTGCATAAGGACAAAGAGGGAAC
TATTATCTATGTAGGTAAAGCTAAGAATTTGAAGAACCGAGTGCGGTCTTATTTTCGTGGTAGCCATGATACCAAAACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTGACCGAATCAAATACTGAGGCTCTCTTGCTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAGTATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GACCTTTCCTCGCTTGCTTATTACGAGACAGATTAAGAAAAATGACGGTCTATATTTCGGGCCCTATCCAGATTCGTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGCATTTTTCCCTTTAAGAAATGTAAAAACCCTGTCAATAAGGTCTGTTTT
TATTACCATTTAGGACAGTGTTGTGCTCATACTATCTGCCATACAGATAAGGCTTATTGGGATGGTCTGGTAGAGGATGT
CAAACACTTTTTGAATGGTAAGGATGACAAGATTATTGATGGGCTGCGGGCAAAAATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCATCATGCGCACCAAGCAGCGGGTGATGAGTAAG
GACTTGCAAGACAGAGATATTTTTGGCTACTTTGTTGACAAGGGCTGGATGTGCGTACAGGTTTTCTTTGTCCGTCAAGG
GAAATTAATTCAGCGGGATGTTAACCTTTTTCCTTACTATAACGAGGCAGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTATCAAGATAAACAGCATTTTATCCCCAAAGAAGTCTTTATTCCAGAAGCTATTGACGAAGAACTAGTAGCGGCCATT
GTGCCAACTAAAATCATCAAGCCTCAACGAGGTGAGAAAAAACAATTGGTGGCTTTGGCGACCAAGAATGCACGTGTTAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCCATTGACAATCTAGGCTACTTGTTAG
GAATTGACAAGCCAGTCCGGATTGAGGCTTTTGATAATTCCAATATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGCCCAGATGATTATGCCAG
CATGAGGGAAGTGATTTTTCGAAGGTATAGCCGCGTTAAACATGAAGGACTGGTAGCTCCTGATTTAATCATCATTGATG
GTGGGCTAGGGCAGGTCAATGCGGCCAGAGAAGTGATTGAAGACCGACTAGGTTTAACGATTCCTATTGCGGGTTTGCAA
AAAAATGATAAGCACCAGACCCATGAATTGCTCTTTGGAAAGCCACTCGAGGTAGTCCCCTTACCCCGTAATTCAGAAGA
ATTTTTCCTCTTGCATCGCATCCAAGATGAGGTGCACCGCTTTGCGATTACTTTCCACCGACAGGTTCGCAGTAAAAATT
CATTCTCTTCGAAATTGGATAAGATTCCAGGACTAGGTCCGAAGCGCAAGCAGATACTGCTTAAACATTTTAAAACCATG
ACAGCCATTGCAGCAGCTAGTCCAGATGAGATTCATTCGTTAGGGATTCCTAGGGCGGTGGCATCAGCTGTCCATCAGCA
TCTGACAGACAGTCAGCAAAGTTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

UvrB/uvrC motif (UVR)

(196-227)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.891

99.158

0.753
  uvrC Streptococcus pneumoniae R6

75.552

99.158

0.749
  uvrC Streptococcus pneumoniae D39

75.552

99.158

0.749