Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I6H78_RS07145 Genome accession   NZ_CP066059
Coordinates   1481978..1483318 (+) Length   446 a.a.
NCBI ID   WP_125418563.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1476978..1488318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS07110 (I6H78_07110) - 1477573..1477860 (-) 288 WP_198459236.1 hypothetical protein -
  I6H78_RS07115 (I6H78_07115) - 1477870..1478280 (-) 411 WP_198459237.1 HIT family protein -
  I6H78_RS07120 (I6H78_07120) pptA 1478348..1479079 (+) 732 WP_198459238.1 ABC transporter ATP-binding protein Regulator
  I6H78_RS07125 (I6H78_07125) pptB 1479076..1480125 (+) 1050 WP_198459239.1 ABC transporter permease Regulator
  I6H78_RS07130 (I6H78_07130) - 1480274..1480603 (-) 330 WP_125418557.1 helicase BlpT -
  I6H78_RS07135 (I6H78_07135) - 1480884..1481222 (+) 339 WP_125418559.1 LytTR family DNA-binding domain-containing protein -
  I6H78_RS07140 (I6H78_07140) comE/blpR 1481227..1481964 (+) 738 WP_198459240.1 response regulator transcription factor Regulator
  I6H78_RS07145 (I6H78_07145) comD/blpH 1481978..1483318 (+) 1341 WP_125418563.1 sensor histidine kinase Regulator
  I6H78_RS07150 (I6H78_07150) blpC 1483598..1483756 (-) 159 WP_125418565.1 quorum-sensing system pheromone BlpC -
  I6H78_RS07155 (I6H78_07155) - 1483813..1485174 (-) 1362 WP_125418567.1 bacteriocin secretion accessory protein -
  I6H78_RS07160 (I6H78_07160) comA/nlmT 1485185..1487338 (-) 2154 WP_198459241.1 peptide cleavage/export ABC transporter BlpA Regulator
  I6H78_RS07165 (I6H78_07165) - 1487619..1487822 (+) 204 WP_125418571.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 52171.08 Da        Isoelectric Point: 5.4019

>NTDB_id=453486 I6H78_RS07145 WP_125418563.1 1481978..1483318(+) (comD/blpH) [Streptococcus oralis strain FDAARGOS_1021]
MELVWKIVYAFLISGLELFIFFKVDGIVLTLERVFKAFLFKILLAVVFVTISYIVGNAYLSYFVEPLYGIGLSFLFLRGF
SKKLLLFYGLFPMILVNLFYRGISYFVLPFLGQGQVYDDLSFIWLFIKIFICFISLAFLKWLDYDFTSLRREILDKDFQK
SLTKINWIMGAYYLVMQSLSYLEYVQDIQSTTIRHLILVFYLLFFMGIIKKLDTYLKEKLQEKLNQEQVLRYREMERYSR
HIEELYKEVRSFRHDYANLLTSLRLGIEEEDMEQIKEVYNSVLKDSVQKFQDNKYDLGRLVNIRDRALKSLLAGKFIKAR
EKDIVFNVEVPEEIQVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGEQEIFIIENSIKEEGIDVSEIFSFG
VSSKGEERGVGLYTVRKIVESYPNASLNTTCQNQVFRQVLTMLSIE

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=453486 I6H78_RS07145 WP_125418563.1 1481978..1483318(+) (comD/blpH) [Streptococcus oralis strain FDAARGOS_1021]
ATGGAATTAGTTTGGAAGATAGTATATGCGTTTTTGATATCTGGATTGGAATTGTTTATATTTTTTAAGGTGGATGGAAT
TGTTCTGACTCTGGAGAGAGTTTTTAAGGCCTTTCTTTTTAAGATACTTTTGGCAGTTGTTTTTGTAACGATTAGCTATA
TAGTAGGAAATGCTTACCTATCTTATTTTGTGGAACCCTTGTACGGCATAGGTTTATCTTTCTTGTTTTTAAGAGGGTTT
TCTAAAAAACTCCTTCTATTTTATGGTCTCTTTCCAATGATATTGGTAAATCTCTTTTATAGAGGAATCTCCTATTTTGT
GCTTCCATTTTTGGGGCAAGGGCAAGTGTACGATGACCTCTCTTTTATTTGGTTATTTATAAAAATTTTCATTTGCTTTA
TTTCTCTAGCCTTTTTGAAATGGTTAGACTATGATTTTACTAGCTTGAGAAGGGAGATTCTAGACAAAGATTTTCAAAAG
TCTCTGACTAAGATTAACTGGATAATGGGAGCCTACTATCTAGTGATGCAAAGTTTGTCTTATTTAGAATATGTACAAGA
TATTCAATCAACGACTATTCGCCATCTGATTCTGGTGTTTTACTTGCTCTTTTTTATGGGGATTATCAAGAAATTGGATA
CCTACTTGAAGGAAAAACTTCAGGAGAAACTGAACCAAGAGCAGGTTTTGCGCTATAGAGAAATGGAGCGGTATAGTCGG
CATATAGAGGAACTTTACAAGGAAGTACGGAGCTTTCGTCATGATTATGCCAACCTCTTGACTAGCCTACGCCTAGGTAT
TGAAGAGGAGGATATGGAGCAGATAAAAGAGGTCTACAACTCCGTTTTAAAGGACTCCGTCCAGAAATTTCAGGACAATA
AATATGACCTTGGACGGTTGGTGAATATTCGTGATCGTGCCCTCAAAAGTCTCCTTGCAGGAAAATTTATAAAAGCCAGA
GAAAAGGATATTGTCTTTAATGTCGAAGTTCCTGAGGAGATTCAAGTTGAGGGGATGAGTCTGCTTGATTTTTTAACTAT
CGTATCTATCCTTTGTGACAATGCTATTGAAGCCAGTGCAGAGGCTAGTCAACCTCATGTTTCAATCGCCTTTTTAAAAA
ATGGAGAACAGGAGATCTTTATCATTGAAAACTCCATCAAAGAAGAGGGCATAGATGTTTCTGAAATCTTCTCTTTTGGA
GTTAGTTCTAAAGGGGAGGAACGAGGTGTTGGTCTCTATACCGTCAGGAAGATTGTTGAAAGTTATCCCAATGCTAGTCT
CAATACAACCTGTCAAAATCAAGTCTTTCGTCAGGTTTTGACAATGTTATCAATTGAATGA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(340-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

39.286

94.17

0.37