Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FOC72_RS01770 Genome accession   NZ_CP054570
Coordinates   357272..357961 (+) Length   229 a.a.
NCBI ID   WP_002894561.1    Uniprot ID   A0A859EM01
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 352272..362961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS01750 (FOC72_01750) - 352310..353368 (+) 1059 WP_002894553.1 DNA cytosine methyltransferase -
  FOC72_RS01755 (FOC72_01755) - 353361..355391 (+) 2031 WP_002894556.1 ATP-binding protein -
  FOC72_RS01760 (FOC72_01760) - 355433..355676 (+) 244 Protein_331 DNA cytosine methyltransferase -
  FOC72_RS01765 (FOC72_01765) gndA 355838..357262 (+) 1425 WP_002894560.1 NADP-dependent phosphogluconate dehydrogenase -
  FOC72_RS01770 (FOC72_01770) covR 357272..357961 (+) 690 WP_002894561.1 response regulator transcription factor Regulator
  FOC72_RS01775 (FOC72_01775) - 358249..360441 (+) 2193 WP_002894565.1 PTS transporter subunit IIBC -
  FOC72_RS01780 (FOC72_01780) - 360459..361274 (+) 816 WP_002894567.1 endonuclease/exonuclease/phosphatase family protein -
  FOC72_RS01785 (FOC72_01785) nrdR 361440..361913 (+) 474 WP_002894570.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26363.41 Da        Isoelectric Point: 5.4491

>NTDB_id=453486 FOC72_RS01770 WP_002894561.1 357272..357961(+) (covR) [Streptococcus sanguinis strain FDAARGOS_770]
MAKRILLVENEKNLARFVSLELQKESFLVDLAETGQEGLALAKDVDYDLLLLNYDLQDMTASDFAKQLSLIKPASVIIVL
ASREEIAEQREAIQHFAVSYVVKPFIISDLVERVSIIFRGRDFIDQHCSLLKIPTSYRNLRVDIKNHTVYRGEEVIALTR
REYDLLVTLMGSNKVLSREQLLERVWKYESATETNVVDVYIRYLRSKIDVEGQPSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=453486 FOC72_RS01770 WP_002894561.1 357272..357961(+) (covR) [Streptococcus sanguinis strain FDAARGOS_770]
ATGGCAAAGCGAATTTTACTAGTAGAAAATGAAAAAAATCTTGCCCGGTTTGTGAGTTTGGAACTGCAAAAGGAAAGCTT
TCTTGTAGATTTAGCTGAGACTGGTCAAGAGGGACTGGCTCTGGCTAAGGATGTGGATTATGACTTGCTCTTGCTCAACT
ATGATCTTCAAGATATGACTGCCAGCGATTTTGCTAAACAGCTGAGCTTGATTAAGCCAGCGTCCGTCATTATCGTTCTG
GCTAGTCGCGAAGAGATTGCAGAGCAGCGGGAAGCAATCCAGCATTTTGCTGTTTCCTACGTAGTCAAGCCCTTCATTAT
CAGTGATTTAGTGGAGCGTGTCTCCATCATTTTCCGCGGTCGTGACTTTATCGACCAGCACTGCAGCCTCTTAAAAATTC
CGACCTCTTACAGGAATCTGCGAGTGGATATTAAAAATCACACAGTTTACCGTGGCGAGGAAGTTATTGCGCTGACGCGG
CGGGAGTACGATCTGCTGGTAACCCTGATGGGCAGCAATAAGGTCCTGAGCCGTGAGCAGCTGCTGGAGCGTGTCTGGAA
GTACGAGAGTGCAACGGAGACCAACGTTGTAGATGTTTATATTCGTTATCTGCGCAGTAAAATTGATGTGGAGGGGCAGC
CAAGCTATATCAAAACCGTTCGCGGTGTTGGTTATGCCATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859EM01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

48.035

100

0.48