Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6H78_RS06045 Genome accession   NZ_CP066059
Coordinates   1252151..1254100 (+) Length   649 a.a.
NCBI ID   WP_198459122.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1247151..1259100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS06025 (I6H78_06025) argR 1247868..1248314 (+) 447 WP_001231483.1 arginine repressor -
  I6H78_RS06030 (I6H78_06030) hexA 1248365..1250899 (+) 2535 WP_198459119.1 DNA mismatch repair protein MutS Machinery gene
  I6H78_RS06035 (I6H78_06035) - 1250942..1251400 (-) 459 WP_198459120.1 DUF3021 domain-containing protein -
  I6H78_RS06040 (I6H78_06040) - 1251397..1251837 (-) 441 WP_198459121.1 LytTR family DNA-binding domain-containing protein -
  I6H78_RS06045 (I6H78_06045) hexB 1252151..1254100 (+) 1950 WP_198459122.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6H78_RS06050 (I6H78_06050) - 1254251..1254748 (-) 498 WP_198460233.1 helix-turn-helix domain-containing protein -
  I6H78_RS06055 (I6H78_06055) ruvA 1254907..1255500 (+) 594 WP_000273410.1 Holliday junction branch migration protein RuvA Machinery gene
  I6H78_RS06060 (I6H78_06060) - 1255510..1256076 (+) 567 WP_198459123.1 DNA-3-methyladenine glycosylase I -
  I6H78_RS06065 (I6H78_06065) - 1256156..1256419 (-) 264 WP_000166112.1 SemiSWEET family transporter -
  I6H78_RS06070 (I6H78_06070) - 1256525..1257559 (-) 1035 WP_198460234.1 S66 peptidase family protein -
  I6H78_RS06075 (I6H78_06075) - 1257834..1258181 (-) 348 WP_198459124.1 hypothetical protein -
  I6H78_RS06080 (I6H78_06080) - 1258197..1258874 (-) 678 WP_198459125.1 DUF1129 domain-containing protein -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73436.94 Da        Isoelectric Point: 5.6226

>NTDB_id=453471 I6H78_RS06045 WP_198459122.1 1252151..1254100(+) (hexB) [Streptococcus oralis strain FDAARGOS_1021]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIPHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIAIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALVSE
AISNSLKEQALIPDALENLAKSTIRNRQKVEQTILPLKENTLYYEKTELSKPSQVEVADHQVELTEEGRDLTLFAKETLN
QLTKPAKLHFAERKPANYDQLDHPELDFASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLRERMALLEEVGVFLAEYGENQFILREHPIWMVEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=453471 I6H78_RS06045 WP_198459122.1 1252151..1254100(+) (hexB) [Streptococcus oralis strain FDAARGOS_1021]
ATGTCTCATATTATTGAATTGCCAGAGGTGCTGGCAAACCAGATCGCGGCAGGAGAGGTCATTGAACGTCCTGCTAGTGT
GGTCAAAGAGTTGGTAGAAAATGCCATTGACGCAGGTTCTAGCCAGATTATCATCGAGATTGAGGAAGCTGGTCTTAAGA
AAATCCAAATCACCGATAATGGTCACGGGATTCCCCACGATGAAGTCGAGTTGGCTCTTCGCCGTCATGCAACTAGTAAG
ATTAAGAATCAGGCAGATCTTTTTCGGATTCGGACTCTCGGTTTTCGTGGTGAAGCTTTGCCTTCTATCGCATCTGTTAG
TGTACTGACTCTTTTGACAGCGGTGGATGGTGCCAGTCACGGGACCAAGCTCGTTGCGCGTGGGGGAGAAGTTGAGGAAG
TTATCCCAGCGACTAGTCCTGTGGGGACCAAAGTTTGTGTGGAGGACCTCTTTTTCAACACACCTGCCCGCCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGCTTGGCCCATCCCGAGATTTCTTT
TAGTTTAATCAGTGATGGAAAGGAAATGACGCGGACAGCAGGGACTGGTCAACTGCGACAAGCAATCGCAGGAATTTATG
GTTTGGCAAGTGCCAAGAAGATGATTGCCATTGAGAACTCTGACTTAGATTTCGAAATTACAGGTTTTGTGTCTCTGCCT
GAGTTAACCCGAGCAAATCGTAACTATATCAGCCTCTTCATCAATGGCCGCTATATCAAGAACTTCTTGCTCAATCGCGC
TATTCTTGACGGTTACGGAAGCAAGCTCATGGTAGGGCGTTTTCCACTGGCTGTCATTCACATCCATATTGATCCTTATC
TGGCTGATGTCAATGTGCATCCAACCAAGCAAGAAGTGCGGATTTCTAAGGAAAGAGAACTGATGGCGCTGGTCTCAGAA
GCCATTTCCAACAGTCTCAAGGAGCAAGCCTTGATCCCTGATGCCTTGGAAAATCTTGCCAAGTCGACCATTCGCAATCG
TCAAAAGGTAGAGCAGACCATTCTCCCACTCAAAGAAAATACGCTTTACTATGAAAAAACAGAACTCTCAAAACCTAGTC
AAGTTGAGGTAGCTGATCACCAGGTTGAATTAACTGAGGAGGGTAGGGACCTAACCCTGTTTGCCAAGGAAACCTTGAAC
CAGCTAACCAAGCCAGCAAAACTGCATTTTGCAGAGAGAAAGCCTGCTAACTACGACCAACTAGACCATCCAGAGTTAGA
TTTTGCTAGCCTCGATAAGGCTTATGACAAGCTGGAGCGAGAAGAATCATCCAGCTTCCCAGAGTTGGAGTTTTTCGGAC
AAATGCACGGGACCTATCTTTTTGCCCAAGGGCGAGATGGCCTCTACATCATAGACCAGCACGCCGCTCAGGAACGAGTT
AAGTACGAGGAATACCGTGAAAGCATTGGCAATGTTGACCAAAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
TCCTGCAGATGATGCTCTTCGTCTCAGGGAAAGAATGGCACTTTTAGAGGAAGTGGGTGTCTTTTTAGCAGAGTACGGAG
AAAATCAATTTATCCTGCGTGAGCATCCTATTTGGATGGTAGAGGAAGAAATCGAGTCTGGTATCTATGAAATGTGCGAC
ATGCTGCTCTTGACCAAGGAAGTTTCGATCAAGAAATACCGAGCAGAGCTAGCCATCATGATGTCCTGCAAGCGGTCTAT
CAAGGCTAACCATCGTATCGATGACCACTCAGCCAGACAACTCCTTTATCAGCTTTCTCAATGTGACAATCCCTATAACT
GTCCCCACGGACGTCCCGTTTTGGTGCATTTTACCAAGTCGGATATGGAAAAGATGTTCCGACGTATTCAGGAAAATCAT
ACCAGTCTTCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

95.84

100

0.958