Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H78_RS02945 Genome accession   NZ_CP066059
Coordinates   602518..604365 (-) Length   615 a.a.
NCBI ID   WP_198459929.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 597518..609365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS02925 (I6H78_02925) pepV 597896..599296 (-) 1401 WP_198459921.1 dipeptidase PepV -
  I6H78_RS02930 (I6H78_02930) - 599306..599911 (-) 606 WP_198459923.1 nitroreductase family protein -
  I6H78_RS02935 (I6H78_02935) - 600037..601668 (-) 1632 WP_198459925.1 hypothetical protein -
  I6H78_RS02940 (I6H78_02940) - 601680..602528 (-) 849 WP_198459927.1 metallophosphoesterase family protein -
  I6H78_RS02945 (I6H78_02945) uvrC 602518..604365 (-) 1848 WP_198459929.1 excinuclease ABC subunit UvrC Machinery gene
  I6H78_RS02950 (I6H78_02950) - 604467..605168 (-) 702 WP_198459931.1 M57 family metalloprotease -
  I6H78_RS02955 (I6H78_02955) - 605273..606052 (-) 780 WP_198459933.1 alpha/beta hydrolase -
  I6H78_RS02960 (I6H78_02960) - 606121..607782 (-) 1662 WP_198459935.1 ribonuclease J -
  I6H78_RS02965 (I6H78_02965) - 608307..608954 (-) 648 WP_198459943.1 COG3942 and LysM peptidoglycan-binding domain-containing protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70716.29 Da        Isoelectric Point: 8.9723

>NTDB_id=453417 I6H78_RS02945 WP_198459929.1 602518..604365(-) (uvrC) [Streptococcus oralis strain FDAARGOS_1021]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAKAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKVL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQEEVELAQVAEERVDYQTEGNYYEP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=453417 I6H78_RS02945 WP_198459929.1 602518..604365(-) (uvrC) [Streptococcus oralis strain FDAARGOS_1021]
ATGAATAACTTGATCAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGTTACATTCACAAAGATAAAAACGGTAC
CATTATCTATGTTGGAAAGGCTAAAAATCTGCGCAACCGCGTGCGCTCCTATTTCCGTGGAAGTCACGATACCAAGACTG
AGGCTCTGGTATCTGAAATTGTGGATTTTGAATTTATCGTCACTGAGTCCAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATTAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGATAAGTCCTATCCCTTCATCAAAATCACCAATGA
GCGTTATCCTCGCTTGATTATCACCCGTCAGGTCAAAAAGGATGGGGGTCTCTACTTTGGTCCCTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTACTGGATCGGATTTTTCCTTTTCGGAAATGTACCAACCCGCCCTCTAAGGTTTGTTTT
TACTACCATATCGGCCAGTGTATGGCCCATACCATCTGTAAAAAAGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
TTCTGATTTCCTAAAAGGGCAGGATGATAAAATTATCGATGACCTTAAGGGTAAGATGGCAAAGGCAGCTCAAAGTATGG
AGTTTGAACGTGCAGCGGAATACCGTGATCTGATTCAGGCCATTGGAACACTTCGGACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGTGATGTCTTTGGCTACTATGTGGACAAGGGCTGGATGTGTGTCCAGGTTTTCTTTGTCCGTCAGGG
AAAACTCATCGAGCGGGATGTCAACCTCTTCCCTTACTACAATGATCCGGATGAGGACTTTTTGACCTACGTGGGACAAT
TTTATCAAGAAAAATCACATCTAGTTCCCAATGAAGTGCTGATTCCGCAGGATATCGATGAAGAAGCAGTCAAGGTCTTG
GTGGATACCAAGATTCTCAAACCTCAGCGTGGTGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCCCGTGTTAG
TCTGGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACTCAAGGGGCAATTGAAAATCTGGGGCGCTTGCTCC
AAATCCCGACCCCAGTCCGTATCGAGTCCTTTGATAACTCTAATATCATGGGAACCAGTCCTGTTTCAGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAAAAAGACTACCGAAAGTACAAGATAAAAACGGTTGTCGGTCCAGATGACTATGCTAG
TATGCGTGAGGTTATTCGCAGACGTTATGGTCGAGTTCAACGTGAGGGTTTAACCCCGCCAGATTTGATTGTCATCGATG
GGGGACAAGGTCAGGTCAATATCGCTAAGCAGGTTATTCAAGAAGAGCTAGGTTTGGACATTCCAATTGCAGGTCTGCAA
AAGAATGACAAGCACCAAACCCATGAACTGCTCTTTGGAGATCCACTGGAAGTGGTGGAGTTATCTCGCAATTCTCAGGA
ATTTTTCTTGCTTCAACGTATCCAAGATGAGGTACACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTTTCATCTCAATTGGATGGGATTGACGGTCTGGGACCTAAACGCAAACAGAATCTCATGAAGCATTTTAAATCTCTC
ACTAAAATCAAGGAAGCCAGTGTGGATGAAATTGTCGAAGTTGGGGTGCCAAGAGCAGTCGCAGAAGCTGTTCAGAGAAA
GTTGAACCCTCAGGAAGAAGTGGAGTTGGCTCAAGTAGCGGAAGAGAGAGTAGATTACCAAACGGAAGGAAACTATTATG
AACCATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.724

100

0.977
  uvrC Streptococcus pneumoniae R6

97.398

100

0.974
  uvrC Streptococcus pneumoniae D39

97.398

100

0.974