Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H72_RS09595 Genome accession   NZ_CP066055
Coordinates   1898424..1900202 (+) Length   592 a.a.
NCBI ID   WP_198457949.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1893424..1905202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS09580 (I6H72_09580) nrdH 1895493..1895711 (-) 219 WP_003023812.1 glutaredoxin-like protein NrdH -
  I6H72_RS09585 (I6H72_09585) - 1896105..1896368 (+) 264 WP_003023815.1 phosphocarrier protein HPr -
  I6H72_RS09590 (I6H72_09590) ptsP 1896370..1898103 (+) 1734 WP_003068445.1 phosphoenolpyruvate--protein phosphotransferase -
  I6H72_RS09595 (I6H72_09595) uvrC 1898424..1900202 (+) 1779 WP_198457949.1 excinuclease ABC subunit UvrC Machinery gene
  I6H72_RS09600 (I6H72_09600) - 1900387..1901211 (+) 825 WP_198457950.1 ABC transporter ATPase -
  I6H72_RS09605 (I6H72_09605) - 1901608..1902213 (+) 606 WP_198457951.1 nitroreductase family protein -
  I6H72_RS09610 (I6H72_09610) pepV 1902233..1903633 (+) 1401 WP_198457952.1 dipeptidase PepV -
  I6H72_RS09615 (I6H72_09615) - 1903689..1904546 (+) 858 WP_198457953.1 SDR family oxidoreductase -
  I6H72_RS09620 (I6H72_09620) - 1904556..1905140 (+) 585 WP_198457954.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 592 a.a.        Molecular weight: 68150.50 Da        Isoelectric Point: 9.2383

>NTDB_id=453386 I6H72_RS09595 WP_198457949.1 1898424..1900202(+) (uvrC) [Streptococcus constellatus strain FDAARGOS_1015]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEVEDFEFIVTESNIEALLLEIN
LIKENQPKYNIMLKDDKSYPFIKITNETYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTICHNDPHFFQEMAQEVADFLKGHDNKIIDELKGKMTSAAEKMEFEKAAEYRDLLQSIATLRTKQRVMAR
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQNKSHLVPNEILIPSDIDEESVRAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGRLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNIAKDVIQHQLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMRHFKSL
ANIKKASVEEIVEVGVPRKVAEAVQTKLHLEV

Nucleotide


Download         Length: 1779 bp        

>NTDB_id=453386 I6H72_RS09595 WP_198457949.1 1898424..1900202(+) (uvrC) [Streptococcus constellatus strain FDAARGOS_1015]
ATGAACAACTTGATTAAATCAAAATTGGAATTATTGCCGACTAGCCCAGGCTGTTATATCCACAAGGATAAAAATGGTAC
GATCATCTATGTAGGAAAAGCTAAGAATCTTCGCAATCGGGTGCGCTCGTATTTTCGCGGAAGTCATGATACTAAAACGG
AAGCGTTAGTGTCTGAGGTTGAGGATTTTGAGTTTATTGTCACTGAGTCTAATATTGAAGCTTTGTTGCTTGAAATCAAT
CTGATCAAGGAAAATCAACCCAAATACAACATCATGCTTAAGGACGATAAGTCCTATCCTTTTATCAAAATTACCAATGA
GACATATCCGCGGCTTATAATCACACGTCAGGTTAAGAAAGATGGTGGTTTATATTTTGGCCCGTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCTTGCTGGATCGCATTTTTCCTTTCCGCAAGTGTACCAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTATCTGCCATAATGATCCACATTTCTTTCAAGAGATGGCTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAATACCGAGATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATGGCAAGG
GATTTACAGAATCGGGATGTCTTTGGTTATTATGTGGACAAAGGATGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTTTGACCTATATTGGACAAT
TTTATCAGAATAAATCTCATCTGGTGCCCAATGAAATTTTGATTCCATCTGATATTGACGAGGAATCAGTACGGGCTGTG
GTGGATACAAAAATTCTCAAGCCTCAACGAGGAGAAAAGAAACAGCTGGTCAATCTGGCAATTAAGAATGCTCAAGTTAG
TTTACAGCAGAAGTTTGACTTATTAGAGAAATCTGTTGAAAAAACGCAAGGAGCAATTGAAAATCTAGGCCGGCTCCTCA
ATATTCCCACTCCAGTTCGGATTGAGTCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATTAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCGGATGACTATGCCAG
TATGCGGGAAGTCATCAAGCGTCGCTACAGCCGAGTTATGCGAGATGGTTTAATACCGCCTGATCTGATTGTCATTGATG
GTGGTCAGGGCCAAGTCAACATTGCTAAAGACGTCATTCAACATCAATTAGGTTTAGATATTCCTATCGCTGGTTTGCAA
AAGAACGACAAGCATCAGACTCATGAATTACTTTTTGGTGATCCATTGGAAGTGGTCGAATTATCTCGCAATTCACAGGA
ATTTTTCCTTTTGCAACGCATCCAAGATGAAGTCCACCGCTTTGCCATTACCTTCCATCGCCAGCTCCGGTCTAAGAATT
CCTTCTCATCACAACTAGATGGCATTGAAGGACTGGGGCCCAAACGCAAGCAAAATCTGATGCGACATTTTAAATCTTTG
GCCAATATCAAGAAAGCTAGTGTTGAGGAAATTGTCGAAGTAGGCGTACCGCGAAAAGTGGCAGAGGCCGTGCAGACCAA
GCTTCACCTAGAAGTCTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

Helix-hairpin-helix domain (HHH_5)

(538-585)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(197-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

89.474

99.493

0.89
  uvrC Streptococcus pneumoniae D39

89.474

99.493

0.89
  uvrC Streptococcus pneumoniae TIGR4

89.474

99.493

0.89