Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I6H72_RS03505 Genome accession   NZ_CP066055
Coordinates   711942..712853 (+) Length   303 a.a.
NCBI ID   WP_232619602.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 706942..717853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS03475 (I6H72_03475) - 707646..707876 (-) 231 WP_006270136.1 Blp family class II bacteriocin -
  I6H72_RS03480 (I6H72_03480) - 708106..708426 (-) 321 WP_198458419.1 hypothetical protein -
  I6H72_RS03485 (I6H72_03485) - 708508..708783 (-) 276 WP_048800278.1 hypothetical protein -
  I6H72_RS03490 (I6H72_03490) - 709460..709681 (-) 222 WP_048800277.1 Blp family class II bacteriocin -
  I6H72_RS03495 (I6H72_03495) - 709913..710626 (+) 714 WP_048800552.1 CPBP family intramembrane glutamic endopeptidase -
  I6H72_RS03500 (I6H72_03500) comE/blpR 710795..711541 (+) 747 WP_041786327.1 response regulator transcription factor Regulator
  I6H72_RS03505 (I6H72_03505) comD/blpH 711942..712853 (+) 912 WP_232619602.1 GHKL domain-containing protein Regulator
  I6H72_RS03510 (I6H72_03510) - 712898..713047 (-) 150 WP_096362645.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I6H72_RS03515 (I6H72_03515) - 713144..714505 (-) 1362 WP_020999319.1 bacteriocin secretion accessory protein -
  I6H72_RS03520 (I6H72_03520) comA/nlmT 714516..716666 (-) 2151 WP_198458310.1 peptide cleavage/export ABC transporter Regulator
  I6H72_RS03525 (I6H72_03525) - 717147..717521 (+) 375 WP_003073369.1 hypothetical protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 34820.09 Da        Isoelectric Point: 7.0704

>NTDB_id=453308 I6H72_RS03505 WP_232619602.1 711942..712853(+) (comD/blpH) [Streptococcus constellatus strain FDAARGOS_1015]
MRLIQYNFKTLKSQKINHNDKKIIIFVNISMIVYHLIVQVLSYLENESNIQTLNFRESLVVLYLILFVSVANYLDRHLRE
RIQNDLMLQKDLQLKNMENYSHHIEELYTEVRNFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIG
RLVHIKNDALKSLLAAKFAQAQEHNVSVSLEVPEDICPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSGNKQVFSI
ENAIKEEHIDMSYIFDAGVSSKGSGRGIGLSNVLAILDRYPNVSLASTSQNYRFQHVLEIYLN

Nucleotide


Download         Length: 912 bp        

>NTDB_id=453308 I6H72_RS03505 WP_232619602.1 711942..712853(+) (comD/blpH) [Streptococcus constellatus strain FDAARGOS_1015]
TTGCGTTTAATTCAATATAATTTTAAGACATTAAAATCTCAAAAAATTAATCACAACGATAAGAAAATTATCATCTTTGT
AAATATCAGCATGATTGTTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAACGAGAGTAACATACAGACACTAA
ATTTTAGAGAAAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCCAATTATTTAGACCGTCATTTACGAGAG
AGAATCCAAAATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAATATGGAAAACTACAGTCATCACATTGAAGAACT
GTACACAGAAGTTCGGAATTTTCGGCATGATTACGCTAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATA
TAGGCATTGTAAAGAATGTTTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGA
CGGTTAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATC
CGTTTCATTGGAGGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCTATTTTGT
GTGATAATGCGATTGAAGCTGCCGCTCCAACTATGACGATTGCTTATGTTTTGTCAGGAAATAAGCAGGTATTCTCCATT
GAAAATGCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGG
AATTGGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCACTTGCTAGCACTAGTCAAAATTATCGTT
TCCAGCATGTCCTTGAAATTTATCTGAATTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(201-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

44.014

93.729

0.413
  comD/comD3 Streptococcus equinus JB1

37.793

98.68

0.373