Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6I16_RS16705 Genome accession   NZ_CP066032
Coordinates   3414581..3415237 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain FDAARGOS_1059     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3409581..3420237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I16_RS16675 (I6I16_16675) dcyD 3410461..3411447 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  I6I16_RS16680 (I6I16_16680) tcyL 3411462..3412130 (+) 669 WP_001158206.1 cystine ABC transporter permease -
  I6I16_RS16685 (I6I16_16685) tcyN 3412127..3412879 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6I16_RS16690 (I6I16_16690) sdiA 3413109..3413831 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  I6I16_RS16695 (I6I16_16695) yecF 3413898..3414122 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6I16_RS16700 (I6I16_16700) yecU 3414109..3414285 (-) 177 WP_000590347.1 protein YecU -
  I6I16_RS27680 - 3414368..3414439 (-) 72 Protein_3295 transcriptional regulator -
  I6I16_RS16705 (I6I16_16705) letA 3414581..3415237 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6I16_RS16710 (I6I16_16710) uvrC 3415234..3417066 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  I6I16_RS16715 (I6I16_16715) pgsA 3417123..3417671 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6I16_RS16735 (I6I16_16735) yecA 3418321..3418986 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=453147 I6I16_RS16705 WP_000611335.1 3414581..3415237(+) (letA) [Escherichia coli strain FDAARGOS_1059]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=453147 I6I16_RS16705 WP_000611335.1 3414581..3415237(+) (letA) [Escherichia coli strain FDAARGOS_1059]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486