Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H77_RS01885 Genome accession   NZ_CP066021
Coordinates   375632..377479 (-) Length   615 a.a.
NCBI ID   WP_001061125.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 370632..382479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS01845 (I6H77_01845) - 370681..370974 (-) 294 WP_000880830.1 hypothetical protein -
  I6H77_RS01850 (I6H77_01850) - 370955..371347 (-) 393 WP_000438034.1 hypothetical protein -
  I6H77_RS01855 (I6H77_01855) - 371329..372546 (-) 1218 WP_000704552.1 hypothetical protein -
  I6H77_RS01860 (I6H77_01860) - 372546..372938 (-) 393 WP_001042358.1 hypothetical protein -
  I6H77_RS01865 (I6H77_01865) - 373059..373208 (-) 150 WP_002874325.1 hypothetical protein -
  I6H77_RS01870 (I6H77_01870) - 373210..373620 (-) 411 WP_000746024.1 hypothetical protein -
  I6H77_RS01875 (I6H77_01875) - 374102..374500 (-) 399 WP_001042357.1 hypothetical protein -
  I6H77_RS01880 (I6H77_01880) - 374788..375642 (-) 855 WP_001015755.1 metallophosphoesterase family protein -
  I6H77_RS01885 (I6H77_01885) uvrC 375632..377479 (-) 1848 WP_001061125.1 excinuclease ABC subunit UvrC Machinery gene
  I6H77_RS01890 (I6H77_01890) - 377581..378282 (-) 702 WP_000498556.1 M57 family metalloprotease -
  I6H77_RS01895 (I6H77_01895) - 378387..379166 (-) 780 WP_000290055.1 alpha/beta hydrolase -
  I6H77_RS01900 (I6H77_01900) - 379235..380896 (-) 1662 WP_000065612.1 ribonuclease J -
  I6H77_RS01905 (I6H77_01905) - 381397..382044 (-) 648 WP_000754473.1 COG3942 and LysM peptidoglycan-binding domain-containing protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70590.15 Da        Isoelectric Point: 8.9918

>NTDB_id=452950 I6H77_RS01885 WP_001061125.1 375632..377479(-) (uvrC) [Streptococcus oralis strain FDAARGOS_1020]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
AKIKEASVDEIVEVGVPRAVAEAVQRKLNPQEEVELAQVAEERVNYQTEGNHHEP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=452950 I6H77_RS01885 WP_001061125.1 375632..377479(-) (uvrC) [Streptococcus oralis strain FDAARGOS_1020]
ATGAATAACTTGATCAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGTTACATTCACAAAGATAAAAACGGCAC
TATCATTTATGTAGGAAAGGCTAAAAATCTGCGCAACCGTGTGCGCTCCTATTTCCGTGGAAGTCATGATACCAAGACTG
AGGCTCTGGTGTCTGAGATTGTGGATTTCGAATTTATCGTTACCGAGTCCAATATCGAGGCCCTCCTGCTGGAAATCAAC
CTCATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGATAAGTCCTATCCCTTTATCAAAATCACCAATGA
ACGCTATCCACGGCTTATTATTACTCGTCAGGTCAAAAAGGATGGAGGGCTTTATTTTGGTCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTGCTGGATCGGATTTTCCCTTTTCGCAAGTGTACCAATCCACCTTCTAAGGTTTGCTTT
TATTACCATATCGGTCAATGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCCATGGCTCAGGAGGT
TTCTGACTTCTTAAAAGGACAGGATGACAAAATCATCGATGATCTCAAGGGTAAAATGGCAGTAGCAGCACAAAGTATGG
AGTTTGAACGTGCAGCGGAATACCGTGACCTGATTCAAGCAATTGGAACACTTCGGACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGGGACGTCTTTGGCTACTATGTGGACAAGGGCTGGATGTGTGTACAGGTTTTCTTTGTTCGTCAAGG
CAAGCTCATCGAGCGCGACGTCAATCTCTTCCCCTACTACAATGATCCGGACGAGGACTTCTTGACCTATGTGGGACAAT
TTTATCAAGAAAAATCTCACCTGGTTCCCAATGAGGTACTGATTCCGCAGGATATCGATGAAGAAGCAGTCAAGGCCTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAAAAAAAGCAACTGGTCAATCTAGCCATAAAAAATGCCCGTGTTAG
TCTGGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTTGAAAAGACCCAAGGAGCTATTGAAAATCTGGGACGCTTGCTCC
AAATCCCGACTCCAGTTCGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACCAGTCCTGTTTCGGCCATGGTGGTC
TTTGTCAATGGCAAACCGAGTAAAAAAGACTACCGAAAGTACAAGATAAAAACGGTTGTCGGTCCAGATGACTATGCTAG
TATGCGTGAGGTTATTCGCAGACGTTATGGCCGAGTTCAACGAGAAGGTTTAACCCCGCCAGATTTGATTGTCATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAAGTCATCCAAGAAGAGCTAGGTTTGGATATCCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGAGTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATTCAAGATGAGGTACACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCAAAAAATT
CCTTTTCTTCACAACTGGATGGGATTGAAGGATTGGGACCTAAACGCAAGCAGAATCTCATGAAGCATTTTAAATCTCTC
GCTAAAATCAAGGAAGCCAGTGTAGATGAGATTGTCGAAGTTGGGGTACCAAGGGCAGTCGCAGAAGCTGTTCAGAGAAA
GTTGAACCCGCAGGAAGAAGTGGAGTTGGCTCAAGTAGCGGAAGAGAGAGTAAATTACCAAACGGAAGGAAATCATCATG
AACCATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(538-584)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.724

100

0.977
  uvrC Streptococcus pneumoniae R6

97.398

100

0.974
  uvrC Streptococcus pneumoniae D39

97.398

100

0.974