Detailed information NTG0045287

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HPAKL117_RS02290
• Genome accession: NC_019560
• Coordinates: 475668..478244 (-)
• Length: 858 a.a.
• NCBI ID: WP_015085629.1
• Uniprot ID: -
• Organism: Helicobacter pylori Aklavik117
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 470668..483244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPAKL117_RS02270 (HPAKL117_02275)	comB10	471576..472778 (-)	1203	WP_015085626.1	DNA type IV secretion system protein ComB10	Machinery gene
HPAKL117_RS02275 (HPAKL117_02280)	-	472775..474412 (-)	1638	WP_015085627.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HPAKL117_RS02280 (HPAKL117_02285)	-	474409..475539 (-)	1131	WP_015085628.1	VirB8/TrbF family protein	-
HPAKL117_RS08400	-	475532..475666 (-)	135	WP_041200005.1	hypothetical protein	-
HPAKL117_RS02290 (HPAKL117_02290)	comB4	475668..478244 (-)	2577	WP_015085629.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HPAKL117_RS02295 (HPAKL117_02295)	-	478244..478480 (-)	237	WP_001183708.1	hypothetical protein	-
HPAKL117_RS02300 (HPAKL117_02300)	comB3	478491..478754 (-)	264	WP_001177715.1	hypothetical protein	Machinery gene
HPAKL117_RS02305 (HPAKL117_02305)	comB2	478765..479049 (-)	285	WP_015085630.1	TrbC/VirB2 family protein	Machinery gene
HPAKL117_RS02310 (HPAKL117_02310)	-	479046..479525 (-)	480	WP_015085631.1	hypothetical protein	-
HPAKL117_RS02315 (HPAKL117_02315)	-	479629..480417 (-)	789	WP_015085632.1	hypothetical protein	-
HPAKL117_RS08405 (HPAKL117_02320)	-	480465..481121 (-)	657	WP_015085633.1	DEAD/DEAH box helicase family protein	-
HPAKL117_RS08565	-	481177..481311 (+)	135	WP_017283918.1	hypothetical protein	-
HPAKL117_RS08410 (HPAKL117_02325)	-	481295..481971 (-)	677	Protein_452	type I restriction endonuclease	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98884.94 Da
• Isoelectric Point: 8.7604

>NTDB_id=45287 HPAKL117_RS02290 WP_015085629.1 475668..478244(-) (comB4) [Helicobacter pylori Aklavik117]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGFYNEGKDFHINPFSLEDSPSNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEEYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLVYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLA

Nucleotide

• Length: 2577 bp

>NTDB_id=45287 HPAKL117_RS02290 WP_015085629.1 475668..478244(-) (comB4) [Helicobacter pylori Aklavik117]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAGGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATATGCAAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAAAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCATGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCTAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCTAATTCATGGGGGGATATGCCTTTATCTGTTTTCAAGAACCTAGACCATAGTC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATAGGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGTTTTATAATGAAGGTA
AAGACTTTCATATCAATCCTTTTTCATTAGAGGATAGCCCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCTCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTTCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGAATATTTAAAATCTTCTTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGTCTATTATGTCTTTCATAAAATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACTGCCGTTAATGAATACAAGGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAACACTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTGCCTAA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.849	98.019	0.459