Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H57_RS05375 Genome accession   NZ_CP065991
Coordinates   1171346..1173172 (-) Length   608 a.a.
NCBI ID   WP_005696421.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain FDAARGOS_1000     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1166346..1178172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H57_RS05355 (I6H57_05355) - 1166837..1167835 (+) 999 WP_005696416.1 iron ABC transporter substrate-binding protein -
  I6H57_RS05360 (I6H57_05360) - 1167933..1169453 (+) 1521 WP_005696417.1 iron ABC transporter permease -
  I6H57_RS05365 (I6H57_05365) - 1169466..1170518 (+) 1053 WP_005696419.1 ABC transporter ATP-binding protein -
  I6H57_RS05370 (I6H57_05370) - 1170556..1171275 (-) 720 WP_005696420.1 TerC family protein -
  I6H57_RS05375 (I6H57_05375) uvrC 1171346..1173172 (-) 1827 WP_005696421.1 excinuclease ABC subunit UvrC Machinery gene
  I6H57_RS05380 (I6H57_05380) kdsB 1173182..1173940 (-) 759 WP_005697219.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  I6H57_RS05385 (I6H57_05385) - 1173950..1174129 (-) 180 WP_005696424.1 Trm112 family protein -
  I6H57_RS05390 (I6H57_05390) lpxK 1174146..1175126 (-) 981 WP_032822464.1 tetraacyldisaccharide 4'-kinase -
  I6H57_RS05395 (I6H57_05395) msbA 1175180..1176928 (-) 1749 WP_005696426.1 lipid A ABC transporter ATP-binding protein/permease MsbA -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69213.04 Da        Isoelectric Point: 8.7399

>NTDB_id=452725 I6H57_RS05375 WP_005696421.1 1171346..1173172(-) (uvrC) [Haemophilus parainfluenzae strain FDAARGOS_1000]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCCAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKTELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=452725 I6H57_RS05375 WP_005696421.1 1171346..1173172(-) (uvrC) [Haemophilus parainfluenzae strain FDAARGOS_1000]
ATGTTTGATTCCAAGAAGTTTCTCTCTGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTCAAAAAGCGACTTTCCAGCTATTTCCGCAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATTGATACGACGATTACTTCTTCTGAAACAGAAGCGTTATTGCTTGAGCATAAT
TTCATTAAGCTTTATCAACCTCGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGCGGAACGAAAAAAATTGCAGGTGAGTATTTCGGGCCTTATCCTCATGCAGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGTTGTGCACCTTGTGTGCCAGGTTATGTGACTGATGAGGAATATAACCA
ACAAGTTGAATTAGCTCGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTACCTCATCGGCAAAATGGAACAGG
CGAGCCGAGACTTAGATTTTGAAGGTGCGGCGCGTTATCGAGATCAAATTCAAGCGGTTCGCGCGGTTATCGAAAAACAA
TTTGTATCCAATGAGCGTTTGGACGACATGGATATTATGTCTATTGCGTATCAGCACGGTTTAGCTTGTGTTCAAGTGAT
GTTTATTCGTCAAGGTAAAGTATTAGGCAATCGCAGTTATTTTCCTAAAGTACCCGCTAACACTGATTTATCCGAACTCA
CAGCAACGTTTGTTGGGCAGTTTTATTTGCAAGGTCATCAGGGCAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
CTAGATGAAAAAACCGAGCTTGAGGCCTTGTTAACTGAACAAGCTGGCCGAAAAGTGGTGATACAAGAATCCGCTAAAGG
CGATAAAGGTAAATATCTGCAACTAGCACAAATTAATGCCAAAGCGGCGTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGCACGAACGTTATCAAGCCCTTTGCGAATTGCTTGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGTCAT
ACGATGGGGAATCAAACTGTAGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGTCGTTTTAA
TATTGAAGGCATTACCGGTGGTGATGACTATGCCGCGATGGAGCAAGCCTTAAAGAAACGTTACGATCGTGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGACAGCTTAATCGCGCCTTAGAGGTTTTTCATCATCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATCGGTGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAAGTGTT
GATTATCAGCAAACAAGATCGTGAGATTCACTTGCCGGATGATAGCCTTGCGCTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGCGGACATCGTCAAAAACGTCAAAAAGCCTTTACCCAAAGTGGCTTAGAAACCATTGAA
GGGGTAGGCGCCAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTACAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCAGTACCCGGTATTTCTAAAGCCTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

UvrB/uvrC motif (UVR)

(210-235)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.793

98.355

0.372
  uvrC Streptococcus pneumoniae R6

37.458

98.355

0.368
  uvrC Streptococcus pneumoniae D39

37.458

98.355

0.368