Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HSZ49_RS05020 Genome accession   NZ_CP054438
Coordinates   1043184..1043813 (+) Length   209 a.a.
NCBI ID   WP_002482846.1    Uniprot ID   A0A380HJV9
Organism   Staphylococcus saprophyticus strain UTI-042y     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1038184..1048813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ49_RS13320 - 1038257..1038547 (+) 291 WP_373995835.1 IS3 family transposase -
  HSZ49_RS04985 (HSZ49_04985) - 1038504..1038788 (+) 285 WP_174543866.1 DDE-type integrase/transposase/recombinase -
  HSZ49_RS13325 (HSZ49_04990) - 1038804..1038956 (+) 153 WP_142760159.1 IS3 family transposase -
  HSZ49_RS04995 (HSZ49_04995) - 1039033..1040019 (-) 987 WP_002482841.1 aromatic acid exporter family protein -
  HSZ49_RS05000 (HSZ49_05000) map 1040194..1040946 (+) 753 WP_011302778.1 type I methionyl aminopeptidase -
  HSZ49_RS05005 (HSZ49_05005) - 1041050..1041436 (+) 387 WP_041079966.1 hypothetical protein -
  HSZ49_RS05010 (HSZ49_05010) liaF 1041453..1042154 (+) 702 WP_011302780.1 cell wall-active antibiotics response protein LiaF -
  HSZ49_RS05015 (HSZ49_05015) vraS 1042151..1043194 (+) 1044 WP_011302781.1 sensor histidine kinase Regulator
  HSZ49_RS05020 (HSZ49_05020) vraR 1043184..1043813 (+) 630 WP_002482846.1 response regulator transcription factor Regulator
  HSZ49_RS05025 (HSZ49_05025) - 1043970..1045142 (-) 1173 WP_002482847.1 YihY/virulence factor BrkB family protein -
  HSZ49_RS05030 (HSZ49_05030) - 1045554..1045838 (-) 285 WP_002482848.1 hypothetical protein -
  HSZ49_RS05035 (HSZ49_05035) - 1045845..1046309 (-) 465 WP_174543867.1 low molecular weight protein-tyrosine-phosphatase -
  HSZ49_RS05040 (HSZ49_05040) - 1046444..1046647 (+) 204 WP_002482850.1 DUF1128 family protein -
  HSZ49_RS05045 (HSZ49_05045) - 1046661..1047899 (+) 1239 WP_174543868.1 aminopeptidase -
  HSZ49_RS05050 (HSZ49_05050) - 1048113..1048634 (+) 522 WP_037538134.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23684.19 Da        Isoelectric Point: 4.6997

>NTDB_id=452490 HSZ49_RS05020 WP_002482846.1 1043184..1043813(+) (vraR) [Staphylococcus saprophyticus strain UTI-042y]
MPIKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPNIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=452490 HSZ49_RS05020 WP_002482846.1 1043184..1043813(+) (vraR) [Staphylococcus saprophyticus strain UTI-042y]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCCACACAATCTGA
TATAGATGTCGTAGGGGAAGGTAAGTCAGGAAAAGATGCAATCGAAAAAGCACATGAACTGAAACCGGACCTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTCGAAGCAACTGAACAAGTTAAAAAAGACTTGCCAAATATTAAAGTTGTC
ATGCTTACGAGTTATATTGAAGATAACGAAGTCTATCGTGCACTTGATTCCGGTGTAGATAGCTATATATTGAAAACAAC
AAGTGCTAGTGATATTGCTGAAGCGATTCGTAAGACTTACAATAATGAGTCAGTATTTGAAGCAGAAGTCCTAGTTAAAA
TGAGAAATAGGATGAAACAACGAGCTGAATTGTATGAAATGCTCACAGAACGTGAAATGGAGATTTTATTACTGATTGCT
AAAGGTTACTCTAACCAAGAGATTGCCAGCGCTTCACATATTACGATTAAAACAGTGAAAACGCATGTAAGTAATATCCT
AAGTAAATTAGAAGTTCAAGATAGAACTCAAGCCGTCATATATGCATTCCAGCACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9