Detailed information NTG0452178

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FOH48_RS22290
• Genome accession: NZ_CP054403
• Coordinates: 4172411..4173211 (+)
• Length: 266 a.a.
• NCBI ID: WP_004145898.1
• Uniprot ID: -
• Organism: Klebsiella pneumoniae strain KCJ3K292
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4167411..4178211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOH48_RS22255 (FOH48_022175)	gspH	4167567..4168082 (+)	516	WP_004191951.1	type II secretion system minor pseudopilin GspH	-
FOH48_RS22260 (FOH48_022180)	gspI	4168079..4168444 (+)	366	WP_002889025.1	type II secretion system minor pseudopilin GspI	-
FOH48_RS22265 (FOH48_022185)	gspJ	4168441..4169037 (+)	597	WP_023279845.1	type II secretion system minor pseudopilin GspJ	-
FOH48_RS22270 (FOH48_022190)	gspK	4169034..4170020 (+)	987	WP_004177385.1	type II secretion system minor pseudopilin GspK	-
FOH48_RS22275 (FOH48_022195)	gspL	4170007..4171200 (+)	1194	WP_143873059.1	type II secretion system protein GspL	-
FOH48_RS22280 (FOH48_022200)	-	4171193..4171678 (+)	486	WP_004145896.1	type II secretion system protein M	-
FOH48_RS22285 (FOH48_022205)	-	4171668..4172414 (+)	747	WP_009309263.1	type II secretion system protein N	-
FOH48_RS22290 (FOH48_022210)	pilD	4172411..4173211 (+)	801	WP_004145898.1	prepilin peptidase	Machinery gene
FOH48_RS22295 (FOH48_022215)	hrpB	4173259..4175688 (-)	2430	WP_004222692.1	ATP-dependent helicase HrpB	-
FOH48_RS22300 (FOH48_022220)	thpR	4175761..4176297 (+)	537	WP_004177389.1	RNA 2',3'-cyclic phosphodiesterase	-
FOH48_RS22305 (FOH48_022225)	sfsA	4176297..4177013 (+)	717	WP_002888848.1	DNA/RNA nuclease SfsA	-
FOH48_RS22310 (FOH48_022230)	dksA	4177176..4177631 (+)	456	WP_002888845.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29389.01 Da
• Isoelectric Point: 8.8894

>NTDB_id=452178 FOH48_RS22290 WP_004145898.1 4172411..4173211(+) (pilD) [Klebsiella pneumoniae strain KCJ3K292]
MTTLAALSLHFPFVWYGFLLLFGLALGSFYNVVIYRLPRMLTQTADDERITLSTPGSSCPQCRQPIAWRDNIPLLSFLWL
GRRARCCQAPIAWSYPLTELATGLLFILAGALLAPGLPLAGGLVLLSFLLILARIDARTQLLPDRLTLPLLWAGLLFNLN
EVYIALPDAVAGAMAGYLALWSVYWLFRLLTGKEALGYGDFKLLAALGAWCGWQVLPQVLLLASASGLVWTLLQRLWTRQ
SLQQPLAFGPWLALAGGGIFLWQQMV

Nucleotide

• Length: 801 bp

>NTDB_id=452178 FOH48_RS22290 WP_004145898.1 4172411..4173211(+) (pilD) [Klebsiella pneumoniae strain KCJ3K292]
ATGACGACACTAGCCGCGTTATCGCTGCACTTTCCCTTTGTCTGGTATGGCTTTCTGCTGCTGTTCGGCCTGGCGCTGGG
CAGCTTTTACAATGTGGTGATCTATCGTCTGCCGCGCATGTTGACCCAGACCGCGGACGACGAGCGGATAACCCTCAGCA
CCCCGGGCTCTTCCTGCCCGCAGTGCCGCCAGCCGATCGCCTGGCGGGACAATATCCCGCTGCTCAGTTTCCTCTGGCTG
GGCCGGCGCGCCCGCTGCTGTCAGGCGCCCATCGCGTGGAGCTATCCGCTGACCGAGCTGGCCACCGGCCTGCTGTTTAT
CCTCGCCGGAGCTTTGCTAGCGCCGGGCCTGCCGCTGGCGGGCGGCCTGGTGCTGCTCTCGTTCCTGCTGATACTGGCGA
GGATTGACGCCCGGACCCAGCTGCTGCCCGATCGCCTGACTCTGCCCCTGCTGTGGGCCGGGCTGCTGTTCAATCTTAAC
GAGGTGTACATTGCCCTGCCGGATGCGGTCGCCGGGGCGATGGCCGGTTATCTGGCGCTGTGGTCGGTCTACTGGCTGTT
CCGCCTGCTGACCGGGAAAGAGGCGCTGGGCTATGGCGATTTTAAGCTGCTGGCGGCGCTGGGCGCCTGGTGCGGCTGGC
AGGTTCTGCCGCAGGTGCTGTTGCTCGCTTCGGCCAGCGGGCTGGTGTGGACCCTGCTGCAACGCCTGTGGACCCGGCAG
TCGCTGCAGCAGCCGCTGGCCTTCGGCCCCTGGCTGGCGCTGGCCGGCGGGGGTATTTTTCTCTGGCAGCAGATGGTCTA
G

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (21-109)

• Type IV leader peptidase family (Peptidase_A24) (123-231)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.434	99.624	0.492
pilD	Vibrio campbellii strain DS40M4	46.182	100	0.477
pilD	Acinetobacter nosocomialis M2	46.008	98.872	0.455
pilD	Acinetobacter baumannii D1279779	45.247	98.872	0.447
pilD	Neisseria gonorrhoeae MS11	43.295	98.12	0.425