Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HRE60_RS02660 Genome accession   NZ_CP054153
Coordinates   536216..537442 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain DB-B5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 531216..542442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS02635 (HRE60_02635) - 531642..532913 (-) 1272 WP_181671043.1 hydroxymethylglutaryl-CoA reductase, degradative -
  HRE60_RS02640 (HRE60_02640) - 532915..534081 (-) 1167 WP_181671044.1 hydroxymethylglutaryl-CoA synthase -
  HRE60_RS02645 (HRE60_02645) - 534552..535412 (+) 861 WP_181671045.1 thymidylate synthase -
  HRE60_RS02650 (HRE60_02650) - 535520..536023 (+) 504 WP_038675550.1 dihydrofolate reductase -
  HRE60_RS02655 (HRE60_02655) - 536028..536198 (+) 171 WP_002886174.1 hypothetical protein -
  HRE60_RS02660 (HRE60_02660) clpX 536216..537442 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HRE60_RS02665 (HRE60_02665) yihA 537452..538051 (+) 600 WP_021144508.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HRE60_RS02670 (HRE60_02670) - 538181..539557 (+) 1377 WP_181671046.1 amino acid permease -
  HRE60_RS02675 (HRE60_02675) mmuM 539569..540519 (+) 951 WP_181671047.1 homocysteine S-methyltransferase -
  HRE60_RS02680 (HRE60_02680) - 540632..540886 (+) 255 WP_002886199.1 DUF1912 family protein -
  HRE60_RS02685 (HRE60_02685) - 540961..541320 (+) 360 WP_181671048.1 helix-hairpin-helix domain-containing protein -
  HRE60_RS02690 (HRE60_02690) plsY 541438..542079 (-) 642 WP_156246547.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=451159 HRE60_RS02660 WP_002890340.1 536216..537442(+) (clpX) [Streptococcus salivarius strain DB-B5]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=451159 HRE60_RS02660 WP_002890340.1 536216..537442(+) (clpX) [Streptococcus salivarius strain DB-B5]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCCTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACTGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCAGCAGATTTTAATATTGAACGTGCGGAACGTGGGATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATTG
AAGGAACAGTAGCCAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATCCAAAAATTTGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGTCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566