Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   HRE60_RS01400 Genome accession   NZ_CP054153
Coordinates   267461..268990 (+) Length   509 a.a.
NCBI ID   WP_014633896.1    Uniprot ID   A0AB33ZGE8
Organism   Streptococcus salivarius strain DB-B5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 262461..273990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS01375 (HRE60_01375) - 262927..263598 (-) 672 WP_181670918.1 TrkA family potassium uptake protein -
  HRE60_RS01380 (HRE60_01380) - 263638..265002 (-) 1365 WP_274602638.1 potassium transporter TrkG -
  HRE60_RS01385 (HRE60_01385) rsmG 265071..265784 (-) 714 WP_181670920.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HRE60_RS01390 (HRE60_01390) - 266083..266619 (+) 537 WP_013990061.1 YceD family protein -
  HRE60_RS01395 (HRE60_01395) covR 266775..267464 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  HRE60_RS01400 (HRE60_01400) covS 267461..268990 (+) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  HRE60_RS01405 (HRE60_01405) nrdR 269112..269591 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  HRE60_RS01410 (HRE60_01410) - 269588..270763 (+) 1176 WP_045771723.1 DnaD domain protein -
  HRE60_RS01415 (HRE60_01415) dnaI 270767..271669 (+) 903 WP_181670921.1 primosomal protein DnaI -
  HRE60_RS01420 (HRE60_01420) der 271774..273084 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  HRE60_RS01425 (HRE60_01425) - 273149..273778 (+) 630 WP_181670922.1 ribonuclease P -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58085.46 Da        Isoelectric Point: 5.1853

>NTDB_id=451151 HRE60_RS01400 WP_014633896.1 267461..268990(+) (covS) [Streptococcus salivarius strain DB-B5]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=451151 HRE60_RS01400 WP_014633896.1 267461..268990(+) (covS) [Streptococcus salivarius strain DB-B5]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACGCTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAGGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCACCTAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGACTCGCCTCCAGGTATGTCCGAGGTAAACAAATTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATCTTCCATGATTTGGAATTCTA
TTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCGACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGGAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAATGGTGAAGGGATTTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGTTGTCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998