Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HRE60_RS01395 Genome accession   NZ_CP054153
Coordinates   266775..267464 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain DB-B5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 261775..272464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS01370 (HRE60_01370) - 262007..262837 (+) 831 WP_181670917.1 energy-coupling factor transporter transmembrane component T -
  HRE60_RS01375 (HRE60_01375) - 262927..263598 (-) 672 WP_181670918.1 TrkA family potassium uptake protein -
  HRE60_RS01380 (HRE60_01380) - 263638..265002 (-) 1365 WP_274602638.1 potassium transporter TrkG -
  HRE60_RS01385 (HRE60_01385) rsmG 265071..265784 (-) 714 WP_181670920.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HRE60_RS01390 (HRE60_01390) - 266083..266619 (+) 537 WP_013990061.1 YceD family protein -
  HRE60_RS01395 (HRE60_01395) covR 266775..267464 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  HRE60_RS01400 (HRE60_01400) covS 267461..268990 (+) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  HRE60_RS01405 (HRE60_01405) nrdR 269112..269591 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  HRE60_RS01410 (HRE60_01410) - 269588..270763 (+) 1176 WP_045771723.1 DnaD domain protein -
  HRE60_RS01415 (HRE60_01415) dnaI 270767..271669 (+) 903 WP_181670921.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=451150 HRE60_RS01395 WP_002883757.1 266775..267464(+) (covR) [Streptococcus salivarius strain DB-B5]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=451150 HRE60_RS01395 WP_002883757.1 266775..267464(+) (covR) [Streptococcus salivarius strain DB-B5]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAACTATTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCGA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCTATCGAAACAAACGTTGTGGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445