Detailed information NTG0450217

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6H01_RS06960
• Genome accession: NZ_CP065613
• Coordinates: 1414393..1416966 (-)
• Length: 857 a.a.
• NCBI ID: WP_038341531.1
• Uniprot ID: -
• Organism: Escherichia coli strain FDAARGOS_944
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1409393..1421966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H01_RS06960 (I6H01_06960)	clpC	1414393..1416966 (-)	2574	WP_038341531.1	ATP-dependent chaperone ClpB	Regulator
I6H01_RS06965 (I6H01_06965)	yfiH	1417096..1417827 (-)	732	WP_038341532.1	purine nucleoside phosphorylase YfiH	-
I6H01_RS06970 (I6H01_06970)	rluD	1417824..1418804 (-)	981	WP_000079112.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
I6H01_RS06975 (I6H01_06975)	comL	1418939..1419676 (+)	738	WP_000197686.1	outer membrane protein assembly factor BamD	Machinery gene
I6H01_RS06980 (I6H01_06980)	raiA	1419952..1420293 (+)	342	WP_000178456.1	ribosome-associated translation inhibitor RaiA	-
I6H01_RS06985 (I6H01_06985)	pheL	1420397..1420444 (+)	48	WP_010723158.1	phe operon leader peptide	-
I6H01_RS06990 (I6H01_06990)	pheA	1420543..1421703 (+)	1161	WP_038341537.1	bifunctional chorismate mutase/prephenate dehydratase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95584.08 Da
• Isoelectric Point: 5.2918

>NTDB_id=450217 I6H01_RS06960 WP_038341531.1 1414393..1416966(-) (clpC) [Escherichia coli strain FDAARGOS_944]
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGD
VQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASS
IRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSKLEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLL
RMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEAL
KLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQ

Nucleotide

• Length: 2574 bp

>NTDB_id=450217 I6H01_RS06960 WP_038341531.1 1414393..1416966(-) (clpC) [Escherichia coli strain FDAARGOS_944]
ATGCGTCTGGATCGTCTTACTAATAAATTCCAGCTTGCTCTTGCCGATGCCCAATCACTTGCACTCGGGCACGACAACCA
ATTCATCGAACCACTTCATTTAATGAGCGCCCTGCTGAATCAGGAAGGGGGTTCGGTTAGTCCTTTATTAACATCCGCTG
GCATAAATGCTGGCCAGTTGCGCACAGATATCAATCAGGCATTAAATCGTTTACCGCAGGTTGAAGGTACTGGTGGTGAT
GTCCAGCCATCACAGGATCTGGTGCGCGTTCTTAATCTTTGCGACAAGCTGGCGCAAAAACGTGGTGATAACTTTATCTC
GTCAGAACTGTTCGTTCTGGCGGCACTTGAGTCTCGCGGCACGCTGGCCGACATCCTGAAAGCAGCAGGGGCGACCACCG
CCAACATTACTCAAGCGATTGAACAAATGCGTGGAGGTGAAAGCGTGAACGATCAAGGTGCTGAAGACCAACGTCAGGCT
TTGAAAAAATATACCATCGATCTTACCGAACGAGCCGAACAAGGCAAACTCGATCCGGTGATTGGTCGTGATGAAGAAAT
TCGCCGTACCATTCAGGTGCTGCAACGTCGTACTAAAAATAACCCGGTACTGATTGGTGAACCCGGCGTCGGTAAAACTG
CCATCGTTGAAGGTCTGGCGCAGCGTATTATCAACGGCGAAGTGCCGGAAGGGTTGAAAGGCCGCCGCGTACTGGCGCTG
GATATGGGCGCGCTGGTGGCTGGGGCGAAATATCGCGGTGAGTTTGAAGAACGTTTAAAAGGCGTGCTTAACGATCTTGC
CAAACAGGAAGGCAACGTCATCCTGTTTATCGACGAATTACATACCATGGTCGGCGCGGGTAAAGCCGATGGCGCAATGG
ACGCCGGAAACATGCTGAAACCGGCGCTGGCGCGTGGTGAATTGCACTGCGTAGGTGCCACGACGCTTGACGAATATCGC
CAGTACATCGAAAAAGATGCTGCGCTGGAACGTCGTTTCCAGAAAGTGTTTGTTGCCGAGCCTTCTGTTGAAGATACCAT
TGCGATTCTACGTGGCCTGAAAGAACGTTACGAATTGCACCACCATGTGCAAATTACTGACCCGGCAATTGTTGCAGCGG
CGACGTTGTCTCATCGCTACATTGCTGACCGTCAGCTGCCGGATAAAGCCATCGACCTGATCGATGAAGCAGCATCCAGC
ATTCGTATGCAGATTGACTCAAAACCAGAAGAACTCGACCGACTCGATCGCCGTATCATCCAGCTCAAACTGGAACAACA
GGCGTTAATGAAAGAGTCTGATGAAGCCAGTAAAAAACGTCTGGATATGCTCAACGAAGAACTGAGCGACAAAGAACGTC
AGTACTCCAAGTTAGAAGAAGAGTGGAAAGCAGAGAAGGCATCGCTTTCTGGTACGCAGACCATTAAAGCGGAACTGGAA
CAGGCGAAAATCGCTATTGAACAGGCTCGCCGTGTGGGGGACCTGGCGCGGATGTCTGAACTGCAATACGGCAAAATCCC
GGAACTGGAAAAGCAACTGGAAGCCGCAACGCAGCTCGAAGGCAAAACTATGCGTCTGTTGCGTAATAAAGTGACCGACG
CCGAAATTGCTGAAGTGCTGGCGCGTTGGACGGGGATTCCGGTTTCTCGCATGATGGAAAGCGAGCGCGAAAAACTGCTG
CGTATGGAGCAAGAACTGCACCATCGCGTTATTGGTCAGAACGAAGCGGTTGATGCGGTATCTAACGCTATTCGTCGTAG
CCGTGCGGGGCTGGCGGATCCAAATCGCCCGATTGGTTCATTCCTGTTCCTCGGCCCAACTGGTGTGGGGAAAACAGAGC
TTTGTAAGGCGCTGGCGAACTTTATGTTTGATAGCGACGAGGCGATGGTCCGTATCGATATGTCCGAGTTTATGGAGAAA
CACTCGGTGTCTCGTCTGGTTGGTGCGCCTCCGGGATATGTCGGTTATGAAGAAGGTGGCTACCTGACCGAAGCTGTGCG
TCGTCGTCCGTATTCCGTCATCCTGTTGGATGAAGTGGAAAAAGCGCATCCGGATGTCTTCAATATTCTGTTGCAGGTAC
TGGATGATGGGCGTCTGACTGACGGGCAGGGGAGAACGGTCGACTTCCGTAATACGGTTGTCATTATGACCTCTAACCTC
GGTTCCGATCTGATTCAGGAACGCTTCGGTGAACTGGATTATGCGCACATGAAAGAGCTGGTGCTCGGTGTGGTTAGCCA
TAACTTCCGTCCGGAATTCATTAACCGTATCGATGAAGTGGTGGTCTTCCATCCGCTGGGTGAACAGCACATTGCGTCGA
TTGCGCAGATTCAGTTGAAACGTCTGTATAAACGTCTGGAAGAACGTGGTTATGAAATCCACATTTCTGACGAGGCGCTG
AAACTGCTGAGCGAGAACGGTTACGATCCGGTCTATGGTGCACGTCCTCTGAAACGTGCAATTCAGCAGCAGATCGAAAA
CCCGCTGGCACAGCAAATACTGTCTGGTGAATTGGTTCCGGGTAAAGTGATTCGCCTGGAAGTTAATGAAGACCGGATTG
TCGCCGTCCAGTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-337)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• AAA lid domain (AAA_lid_9) (342-443)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.685	100	0.463
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.459	100	0.427
clpE	Streptococcus pneumoniae R6	47.717	79.23	0.378
clpE	Streptococcus pneumoniae TIGR4	47.717	79.23	0.378
clpE	Streptococcus pneumoniae D39	47.717	79.23	0.378
clpE	Streptococcus pneumoniae Rx1	47.717	79.23	0.378
clpE	Streptococcus mutans UA159	46.491	79.813	0.371