Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H05_RS01500 Genome accession   NZ_CP065604
Coordinates   308255..310084 (-) Length   609 a.a.
NCBI ID   WP_005567177.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain FDAARGOS_948     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 303255..315084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H05_RS01480 (I6H05_01480) - 303974..305043 (+) 1070 Protein_290 ABC transporter ATP-binding protein -
  I6H05_RS01485 (I6H05_01485) - 305040..305909 (+) 870 WP_005567173.1 ABC transporter permease -
  I6H05_RS01490 (I6H05_01490) - 305906..306757 (+) 852 WP_025298357.1 ABC transporter permease -
  I6H05_RS01495 (I6H05_01495) - 306777..307868 (+) 1092 WP_025298358.1 extracellular solute-binding protein -
  I6H05_RS01500 (I6H05_01500) uvrC 308255..310084 (-) 1830 WP_005567177.1 excinuclease ABC subunit UvrC Machinery gene
  I6H05_RS01505 (I6H05_01505) kdsB 310223..310996 (-) 774 WP_025298359.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  I6H05_RS01510 (I6H05_01510) - 310998..311177 (-) 180 WP_005567179.1 Trm112 family protein -
  I6H05_RS01515 (I6H05_01515) lpxK 311199..312173 (-) 975 WP_005567180.1 tetraacyldisaccharide 4'-kinase -
  I6H05_RS01520 (I6H05_01520) msbA 312192..313940 (-) 1749 WP_005567181.1 lipid A ABC transporter ATP-binding protein/permease MsbA -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69083.11 Da        Isoelectric Point: 9.5140

>NTDB_id=450073 I6H05_RS01500 WP_005567177.1 308255..310084(-) (uvrC) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
MTFDAKKFLANVPHLPGVYRMYDDKSTVIYVGKAKDLKKRLSSYFRKQLSSKKTEALVASIQHIETTITTSETEALLLEH
NYIKTYQPRYNVLLRDDKSYPYILLTKETHPRITAYRGSKKIQGEYFGPYPNAGAVRETLSLLQKLFPIRQCENSVYNNR
SRPCLQYQIGRCLAPCVKGYVTDEAYAQQVNFARLFLQGKDQQVLDHLVKQMEQASQQLNFEEAARVRDQIQAVRAVIEK
QFVANDRHDDIDIIAITYQLGVACVQVLFIRQGKILGNRSYFPKVPSNTNLAELTETFVGQFYLQAHQGRTIPNTIIVDQ
KLDEKVDLETLLSDQAGRKVSIQDHAKGDKSKYLQLAQMNAKAALVTKLKQSTLQHDRYVALQELLGIAAIKRMECFDIS
HTMGEQTTASCVVFNQDGPLKSDYRRFNISGITKGDDYAAMEQALLKRYDKDLEDDKIPDIIFIDGGKGQLNRALQVFEN
LNVKWNKNQPHLIGVAKGVDRRAGLETLILSKWDKELHLPADSLALHLIQHIRDESHNHAISGHRKKRQQHFTQSGLESI
EGVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLQH

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=450073 I6H05_RS01500 WP_005567177.1 308255..310084(-) (uvrC) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
ATGACTTTCGACGCCAAAAAATTCCTCGCCAACGTACCGCACTTACCGGGCGTTTATCGTATGTATGACGATAAAAGCAC
GGTGATTTATGTGGGCAAGGCGAAAGATCTGAAAAAACGCTTATCCAGTTATTTTCGCAAGCAGTTAAGCAGCAAAAAAA
CGGAAGCATTGGTGGCGTCGATTCAGCATATCGAAACCACCATTACCACATCGGAAACCGAAGCCCTGCTCCTAGAGCAC
AATTACATCAAAACCTACCAGCCGCGCTATAACGTGCTGTTGCGCGATGATAAATCTTATCCGTACATTTTATTAACCAA
AGAAACCCACCCGCGTATTACCGCTTATCGCGGTTCGAAAAAAATCCAAGGGGAATATTTCGGTCCTTATCCGAATGCCG
GTGCAGTGCGCGAAACCCTGTCTTTATTACAAAAACTGTTCCCCATTCGGCAGTGTGAAAACTCCGTGTATAACAACCGT
TCGCGCCCCTGTTTGCAGTATCAAATCGGGCGTTGTCTGGCGCCTTGCGTAAAGGGCTATGTGACCGATGAAGCCTATGC
GCAGCAGGTCAATTTCGCCCGCTTGTTTTTACAAGGAAAAGATCAACAGGTGCTGGATCATTTGGTGAAGCAAATGGAAC
AGGCAAGTCAGCAACTGAATTTTGAAGAAGCGGCACGCGTTCGTGATCAAATTCAGGCAGTGCGGGCAGTAATTGAAAAA
CAATTTGTCGCCAACGATCGCCATGACGACATTGATATTATCGCCATCACCTATCAACTCGGCGTGGCCTGCGTGCAGGT
TTTGTTTATTCGTCAAGGTAAGATTTTGGGCAATCGCAGCTATTTTCCGAAAGTCCCGAGCAATACCAATCTGGCAGAAC
TCACGGAAACCTTTGTGGGGCAATTTTATTTGCAGGCGCACCAAGGCAGAACCATTCCGAACACCATTATCGTGGATCAA
AAACTGGACGAAAAAGTCGATTTGGAAACTTTACTCAGCGACCAAGCGGGACGCAAAGTCAGCATTCAGGATCATGCCAA
AGGCGATAAAAGCAAATATTTGCAACTGGCACAAATGAACGCCAAAGCGGCGTTAGTCACCAAATTAAAACAATCCACAT
TACAGCACGATCGCTACGTCGCACTGCAGGAATTACTCGGCATCGCTGCCATCAAACGCATGGAATGTTTCGACATCAGC
CACACCATGGGCGAACAAACCACCGCCTCCTGCGTGGTTTTCAACCAAGACGGACCGCTGAAATCCGATTACCGCCGTTT
CAACATCAGCGGCATCACCAAAGGCGACGATTACGCCGCCATGGAACAAGCCCTGTTAAAACGCTACGACAAAGATCTGG
AAGACGACAAAATTCCCGACATTATTTTTATCGACGGCGGCAAGGGACAACTCAACCGCGCGTTGCAGGTGTTCGAAAAC
CTTAATGTAAAATGGAACAAAAACCAACCGCACTTAATCGGTGTTGCCAAAGGCGTGGATCGTCGTGCCGGTTTGGAAAC
CTTGATTTTGAGCAAATGGGACAAAGAATTGCATTTACCGGCGGACAGCCTTGCGCTTCACTTGATCCAGCATATCCGCG
ACGAAAGCCACAATCACGCCATTAGCGGACACCGCAAAAAACGCCAACAACATTTCACCCAAAGTGGCTTGGAAAGCATT
GAAGGCGTCGGCGCCAAACGCCGCCAAGCCCTGCTCAAATACCTCGGCGGCTTGCAAGGCGTCAAAAATGCCACCCTCGA
CGAAATCGCCTCCGTCCCCGGCATATCAAAAGCCCTGGCAGAAAAGATTTTTGAGACCTTGCAGCATTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-91)

UvrB/uvrC motif (UVR)

(203-236)

Helix-hairpin-helix domain (HHH_5)

(557-608)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.52

100

0.378
  uvrC Streptococcus pneumoniae R6

37.194

100

0.374
  uvrC Streptococcus pneumoniae D39

37.194

100

0.374