Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FOC71_RS08985 Genome accession   NZ_CP053999
Coordinates   1775154..1775843 (-) Length   229 a.a.
NCBI ID   WP_003071837.1    Uniprot ID   A0A3R9LG80
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770154..1780843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS08965 (FOC71_08965) - 1770636..1771118 (+) 483 WP_003071844.1 hypothetical protein -
  FOC71_RS08970 (FOC71_08970) - 1771170..1771985 (-) 816 WP_003071843.1 endonuclease/exonuclease/phosphatase family protein -
  FOC71_RS08975 (FOC71_08975) - 1772003..1774192 (-) 2190 WP_037584494.1 PTS transporter subunit IIBC -
  FOC71_RS08980 (FOC71_08980) - 1774404..1774847 (-) 444 Protein_1753 PTS glucose transporter subunit IIA -
  FOC71_RS08985 (FOC71_08985) covR 1775154..1775843 (-) 690 WP_003071837.1 response regulator transcription factor Regulator
  FOC71_RS08990 (FOC71_08990) gndA 1775852..1777276 (-) 1425 WP_003071834.1 NADP-dependent phosphogluconate dehydrogenase -
  FOC71_RS08995 (FOC71_08995) - 1777368..1777904 (-) 537 WP_003071832.1 DUF177 domain-containing protein -
  FOC71_RS09000 (FOC71_09000) - 1778092..1779318 (+) 1227 WP_003071830.1 hypothetical protein -
  FOC71_RS09005 (FOC71_09005) htpX 1779421..1780317 (-) 897 WP_003071828.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26549.61 Da        Isoelectric Point: 6.5002

>NTDB_id=450032 FOC71_RS08985 WP_003071837.1 1775154..1775843(-) (covR) [Streptococcus intermedius strain FDAARGOS_769]
MGKRILLVENEKKLAQFISLELQNEGYRVDLFETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVGKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=450032 FOC71_RS08985 WP_003071837.1 1775154..1775843(-) (covR) [Streptococcus intermedius strain FDAARGOS_769]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTTTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTAAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTGAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGGAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGTCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCTGTCGAGACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGCAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACTGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-82)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LG80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45