Detailed information NTG0449803

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: STCNRZ1202_RS07460
• Genome accession: NZ_CP065506
• Coordinates: 1428534..1430633 (-)
• Length: 699 a.a.
• NCBI ID: WP_141326678.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1202
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1423534..1435633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1202_RS07425 (STCNRZ1202_07445)	pptB	1424000..1425037 (-)	1038	WP_347229597.1	ABC transporter permease	Regulator
STCNRZ1202_RS07430 (STCNRZ1202_07450)	pptA	1425034..1425765 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
STCNRZ1202_RS07435 (STCNRZ1202_07455)	-	1425830..1426249 (+)	420	WP_011227486.1	HIT family protein	-
STCNRZ1202_RS07440 (STCNRZ1202_07460)	-	1426246..1426554 (+)	309	WP_116920336.1	hypothetical protein	-
STCNRZ1202_RS07445	-	1427106..1427276 (-)	171	WP_011226439.1	hypothetical protein	-
STCNRZ1202_RS07450 (STCNRZ1202_07470)	-	1427346..1427981 (-)	636	WP_011681533.1	DUF4230 domain-containing protein	-
STCNRZ1202_RS07455	-	1428000..1428125 (-)	126	WP_011681534.1	hypothetical protein	-
STCNRZ1202_RS07460 (STCNRZ1202_07475)	clpE	1428534..1430633 (-)	2100	WP_141326678.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STCNRZ1202_RS07465 (STCNRZ1202_07480)	-	1431348..1432439 (-)	1092	WP_347229598.1	nucleotidyltransferase	-
STCNRZ1202_RS07470 (STCNRZ1202_07485)	-	1432446..1433186 (-)	741	WP_300975810.1	class I SAM-dependent methyltransferase	-
STCNRZ1202_RS07475 (STCNRZ1202_07490)	rsfS	1433511..1433864 (-)	354	WP_011227491.1	ribosome silencing factor	-
STCNRZ1202_RS07480 (STCNRZ1202_07495)	yqeK	1433888..1434478 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
STCNRZ1202_RS07485 (STCNRZ1202_07500)	-	1434475..1435107 (-)	633	WP_065972527.1	nicotinate-nucleotide adenylyltransferase	-
STCNRZ1202_RS07490 (STCNRZ1202_07505)	yhbY	1435211..1435528 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77168.05 Da
• Isoelectric Point: 4.8262

>NTDB_id=449803 STCNRZ1202_RS07460 WP_141326678.1 1428534..1430633(-) (clpE) [Streptococcus thermophilus strain CNRZ1202]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=449803 STCNRZ1202_RS07460 WP_141326678.1 1428534..1430633(-) (clpE) [Streptococcus thermophilus strain CNRZ1202]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTAAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTAACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TAGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTAGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTAGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• AAA lid domain (AAA_lid_9) (255-349)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.781	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.062	91.559	0.449
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.576	90.415	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	46.13	92.418	0.426
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.274	88.269	0.382
clpC	Streptococcus mutans UA159	42.995	88.841	0.382