Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   STCNRZ1202_RS00335 Genome accession   NZ_CP065506
Coordinates   58257..60200 (+) Length   647 a.a.
NCBI ID   WP_347229651.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ1202     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 53257..65200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1202_RS00305 (STCNRZ1202_00305) argR 53461..53889 (+) 429 WP_024704313.1 arginine repressor -
  STCNRZ1202_RS00310 (STCNRZ1202_00310) - 53889..54248 (+) 360 WP_347229650.1 YlbF family regulator -
  STCNRZ1202_RS00315 (STCNRZ1202_00315) hexA 54241..56799 (+) 2559 WP_232974677.1 DNA mismatch repair protein MutS Machinery gene
  STCNRZ1202_RS00320 (STCNRZ1202_00320) - 56833..57288 (-) 456 Protein_42 DUF3021 domain-containing protein -
  STCNRZ1202_RS00325 (STCNRZ1202_00325) - 57285..57676 (-) 392 Protein_43 LytTR family DNA-binding domain-containing protein -
  STCNRZ1202_RS00330 (STCNRZ1202_00330) - 57900..58205 (+) 306 WP_014621013.1 hypothetical protein -
  STCNRZ1202_RS00335 (STCNRZ1202_00335) hexB 58257..60200 (+) 1944 WP_347229651.1 DNA mismatch repair endonuclease MutL Machinery gene
  STCNRZ1202_RS00340 (STCNRZ1202_00340) - 60330..60551 (+) 222 WP_002949052.1 hypothetical protein -
  STCNRZ1202_RS00345 (STCNRZ1202_00345) ruvA 60703..61293 (+) 591 WP_002949053.1 Holliday junction branch migration protein RuvA Machinery gene
  STCNRZ1202_RS00350 (STCNRZ1202_00350) - 61300..61854 (+) 555 WP_011225284.1 DNA-3-methyladenine glycosylase I -
  STCNRZ1202_RS00355 (STCNRZ1202_00355) cinA 61950..63221 (+) 1272 WP_084829277.1 competence/damage-inducible protein A Machinery gene
  STCNRZ1202_RS00360 (STCNRZ1202_00360) recA 63257..64396 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  STCNRZ1202_RS00365 (STCNRZ1202_00365) spx 64573..64971 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72464.69 Da        Isoelectric Point: 6.1305

>NTDB_id=449729 STCNRZ1202_RS00335 WP_347229651.1 58257..60200(+) (hexB) [Streptococcus thermophilus strain CNRZ1202]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEVYGTKLVAKGGEIESQDSISTPVGTKITVEKLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALIKS
AIAQSLREQDLIPDALENLAKSSTRGATRSVQTSLPLKQTNLYYDSSRNDFFVTPETVQEDIKPLVSKSESSVSSVANKQ
QPTVKQAKRSADDSDSEHGKLDYKNKSKLKRILENLTNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGVVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVCIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=449729 STCNRZ1202_RS00335 WP_347229651.1 58257..60200(+) (hexB) [Streptococcus thermophilus strain CNRZ1202]
ATGCCAAAAATTATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGTGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAAGCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACGAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACACTTGGTTTTCGAGGTGAAGCCCTACCCTCTATAGCTTCTATTAG
TCACCTTACCATTGTGACAGCAGCGGATGGAGAAGTCTATGGGACAAAACTTGTTGCTAAAGGTGGAGAAATTGAGAGTC
AAGATTCTATTTCAACCCCAGTGGGAACAAAGATTACAGTTGAAAAATTGTTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAACCGTTTGAGTTTAGCCCACCCCGAAGTAGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTTCGCCAAGCTATTGCAGGGATTTATG
GCTTAACAACAGCAAAAAAAATGGTGGAAATTTCAAATTCCGACCTTGATTTTGAAGTTTCTGGTTATGTCAGTCTCCCT
GAATTAACGCGTGCTAACCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTCCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTTATGGTGGGACGCTTCCCAATTGCAGTTATTGATATTCAGATTGATCCTTATT
TGGCAGATGTCAATGTTCACCCAACAAAGCAAGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAAATCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCAAAGTCAAGTACTAGAGGTGC
AACTAGGTCAGTTCAGACGAGTCTCCCACTCAAACAAACCAATCTTTACTATGACAGTAGCCGTAATGATTTCTTTGTCA
CGCCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAAAGTCAGAGTCTTCAGTTTCATCGGTAGCAAACAAACAG
CAACCTACTGTTAAACAGGCAAAACGTTCAGCAGATGATAGTGATAGCGAACACGGAAAACTTGACTATAAAAATAAATC
GAAATTGAAGCGCATACTTGAAAATCTGACCAATGAGGAAACATCAACCTTTCCTGAATTGGAGTTCTTTGGTCAAATGC
ATGGAACCTACCTCTTTGCCCAAGGACAAGGTGGCCTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATAGGTGTGGTTGATAGTAGTTTACAACAACTTTTGGTTCCCTATCTTTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAACCAAGTTTGCATCTATTTGGAGCCTTATGGGAATAATA
CCTTCATTCTTCGAGAGCACCCTATCTGGATGAAGGAAGAAGAAATCGAATCTGCAGTCTATGAGATGTGTGATATGCTT
CTTTTGACGAACGAAGTATCCGTCAAGACCTATCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATAAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAATCCCTATAATTGTCCTC
ACGGCCGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAGAAAATGTTCCGTCGTATTCAAGAAAACCATACCAGC
CTACGTGATTTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(448-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-125)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.95

100

0.7