Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ST4147_RS07805 Genome accession   NZ_CP065504
Coordinates   1495360..1496091 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4147     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1490360..1501091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4147_RS07790 (ST4147_07790) - 1490622..1492889 (+) 2268 WP_011227515.1 Xaa-Pro dipeptidyl-peptidase -
  ST4147_RS07795 (ST4147_07795) - 1493323..1494722 (+) 1400 Protein_1482 IS3-like element ISSth1b family transposase -
  ST4147_RS07800 (ST4147_07800) - 1494868..1495110 (-) 243 WP_011227518.1 Blp family class II bacteriocin -
  ST4147_RS07805 (ST4147_07805) comE/blpR 1495360..1496091 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  ST4147_RS07810 comD/blpH 1496628..1497431 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  ST4147_RS07815 (ST4147_07815) - 1497449..1497610 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST4147_RS07820 (ST4147_07820) - 1497625..1498993 (-) 1369 Protein_1487 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=449698 ST4147_RS07805 WP_002948869.1 1495360..1496091(+) (comE/blpR) [Streptococcus thermophilus strain 4147]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=449698 ST4147_RS07805 WP_002948869.1 1495360..1496091(+) (comE/blpR) [Streptococcus thermophilus strain 4147]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCGGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAAATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362