Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   STAVA116_RS05830 Genome accession   NZ_CP065498
Coordinates   1125389..1127176 (-) Length   595 a.a.
NCBI ID   WP_087010014.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA116     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1120389..1132176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA116_RS05810 (STAVA116_05770) - 1121352..1121994 (-) 643 Protein_1102 DNA alkylation repair protein -
  STAVA116_RS05815 (STAVA116_05775) - 1122186..1122698 (-) 513 WP_022096706.1 GNAT family N-acetyltransferase -
  STAVA116_RS05820 (STAVA116_05780) - 1122857..1123658 (+) 802 Protein_1104 ISL3 family transposase -
  STAVA116_RS05825 (STAVA116_05785) cls 1123750..1125300 (-) 1551 WP_172838694.1 cardiolipin synthase -
  STAVA116_RS05830 (STAVA116_05790) uvrC 1125389..1127176 (-) 1788 WP_087010014.1 excinuclease ABC subunit UvrC Machinery gene
  STAVA116_RS05835 (STAVA116_05795) - 1127236..1127931 (-) 696 WP_087010015.1 YjjG family noncanonical pyrimidine nucleotidase -
  STAVA116_RS05840 (STAVA116_05800) sdaAB 1128209..1128880 (+) 672 WP_087010016.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  STAVA116_RS05845 (STAVA116_05805) sdaAA 1128893..1129762 (+) 870 WP_087010017.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  STAVA116_RS05850 - 1129946..1130178 (+) 233 Protein_1110 IS30 family transposase -
  STAVA116_RS05855 (STAVA116_05810) - 1131197..1131981 (-) 785 Protein_1111 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68556.03 Da        Isoelectric Point: 9.5291

>NTDB_id=449362 STAVA116_RS05830 WP_087010014.1 1125389..1127176(-) (uvrC) [Streptococcus thermophilus strain AVA116]
MNDLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDAGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRIIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=449362 STAVA116_RS05830 WP_087010014.1 1125389..1127176(-) (uvrC) [Streptococcus thermophilus strain AVA116]
ATGAATGATCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCTAAATTTAACATTCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTTTATTTTGGTCCCTACCCAGATGCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTCTGTTTC
TACTACCATATTGGTCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCAGTGTCGACGCTCAGGACCAAACAAAGGATTATCCGTCAA
GATATGCAGGACCGCGATATTTTCGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAGGTTTTCTTTGTCCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAGGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTAGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCCCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae R6

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae D39

75.804

99.328

0.753