Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ST4067_RS06025 Genome accession   NZ_CP065496
Coordinates   1145754..1147541 (-) Length   595 a.a.
NCBI ID   WP_263604410.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4067     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1140754..1152541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4067_RS06005 (ST4067_06015) - 1141716..1142358 (-) 643 Protein_1125 DNA alkylation repair protein -
  ST4067_RS06010 (ST4067_06020) - 1142550..1143062 (-) 513 WP_263604409.1 GNAT family N-acetyltransferase -
  ST4067_RS09720 - 1143221..1143358 (+) 138 WP_011225833.1 hypothetical protein -
  ST4067_RS06015 (ST4067_06025) - 1143340..1144023 (+) 684 Protein_1128 transposase -
  ST4067_RS06020 (ST4067_06030) cls 1144115..1145665 (-) 1551 WP_179970536.1 cardiolipin synthase -
  ST4067_RS06025 (ST4067_06035) uvrC 1145754..1147541 (-) 1788 WP_263604410.1 excinuclease ABC subunit UvrC Machinery gene
  ST4067_RS06030 (ST4067_06040) - 1147601..1148296 (-) 696 WP_263604411.1 YjjG family noncanonical pyrimidine nucleotidase -
  ST4067_RS06035 (ST4067_06045) - 1148623..1149057 (+) 435 WP_263604412.1 biotin transporter BioY -
  ST4067_RS06040 (ST4067_06050) - 1149292..1149918 (-) 627 WP_002948550.1 ABC transporter permease -
  ST4067_RS06045 (ST4067_06055) - 1149923..1150678 (-) 756 WP_002948547.1 ABC transporter ATP-binding protein -
  ST4067_RS06050 (ST4067_06060) - 1150690..1151607 (-) 918 WP_002948546.1 glycine betaine ABC transporter substrate-binding protein -
  ST4067_RS06055 (ST4067_06065) - 1151604..1152263 (-) 660 WP_002948542.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68539.97 Da        Isoelectric Point: 9.5291

>NTDB_id=449260 ST4067_RS06025 WP_263604410.1 1145754..1147541(-) (uvrC) [Streptococcus thermophilus strain 4067]
MNDLIKHKLELLPNSPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCKAHTICHTTEAYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNIFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=449260 ST4067_RS06025 WP_263604410.1 1145754..1147541(-) (uvrC) [Streptococcus thermophilus strain 4067]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAGCCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCCTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTCTGTTTC
TACTACCATATTGGTCAATGTAAGGCTCACACCATCTGTCACACCACCGAAGCCTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATATTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTAGCAACGAAAAATGCCCG
TGTCAGCCTGACCCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(540-590)

GIY-YIG catalytic domain (GIY-YIG)

(17-87)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.481

99.328

0.76
  uvrC Streptococcus pneumoniae R6

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae D39

76.142

99.328

0.756