Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   FOC66_RS06975 Genome accession   NZ_CP053939
Coordinates   1477763..1479895 (-) Length   710 a.a.
NCBI ID   WP_003748961.1    Uniprot ID   -
Organism   Neisseria mucosa strain FDAARGOS_758     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1472763..1484895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC66_RS06950 (FOC66_06950) - 1473158..1473724 (+) 567 WP_003748949.1 NADPH-dependent FMN reductase -
  FOC66_RS06955 (FOC66_06955) - 1473870..1474547 (+) 678 WP_003748951.1 response regulator -
  FOC66_RS06960 (FOC66_06960) - 1474577..1475890 (+) 1314 WP_003748954.1 ATP-binding protein -
  FOC66_RS06965 (FOC66_06965) aroB 1476017..1477096 (-) 1080 WP_003748957.1 3-dehydroquinate synthase -
  FOC66_RS10755 (FOC66_06970) - 1477118..1477630 (-) 513 WP_036494019.1 shikimate kinase -
  FOC66_RS06975 (FOC66_06975) pilQ 1477763..1479895 (-) 2133 WP_003748961.1 type IV pilus secretin PilQ Machinery gene
  FOC66_RS06980 (FOC66_06980) pilP 1479916..1480458 (-) 543 WP_003748964.1 pilus assembly protein PilP Machinery gene
  FOC66_RS06985 (FOC66_06985) pilO 1480474..1481145 (-) 672 WP_003748967.1 type 4a pilus biogenesis protein PilO -
  FOC66_RS06990 (FOC66_06990) pilN 1481145..1481768 (-) 624 WP_003748969.1 PilN domain-containing protein Machinery gene
  FOC66_RS06995 (FOC66_06995) pilM 1481773..1482864 (-) 1092 WP_003748971.1 type IV pilus assembly protein PilM -

Sequence

Protein


Download         Length: 710 a.a.        Molecular weight: 77974.09 Da        Isoelectric Point: 9.5277

>NTDB_id=449260 FOC66_RS06975 WP_003748961.1 1477763..1479895(-) (pilQ) [Neisseria mucosa strain FDAARGOS_758]
MKTKHMTKLFAGFSVALAVQTAFAGNITDINVSTLPDNQKIIKIRFDKDVTTPHGFVTSTPARIALDFANTNIRLPQPVL
EYADPLLHQITAAQNNDRARVVLGLNKISQYNTEIRDNEVWVFVNESTDQTNAAVANERAATPSTARAAQTYQAVSAANI
DFRKGARNSGIIELSAPGFSGQPDIKQQRDRVVVTLKNHTLPTQAQRSLDVADFNTPVQNVTLKRIGNSTQLIIRNNNAN
WDINTKASSGRFVFEVSPKAANTESGGLNQNANKSFKGRKISLDFQDVEVRTILQILAKESGVNIVASDTVKGTMTLSLK
EVPWDQALDLVMQARNLDMRRQGNIINIAPRDELLAKDKAFLQAEKEIAELGPLYSQTFQLKYKNVEEFRKILRLEEYDS
NNSNTRNTLLSNRGSALIDPATNTLIVTDNRGVIEKFRKLIDELDVPTRQVMVEARIVEAEDTFFRNLGVKFGSGGASGR
TAWGSNWSNAQANHNTNASFNRGDVGYPTWSLDPNVSLPTAAAVNSIALVRAFSSGALGLEISASEEQGKSKTISNPRVL
TQDRKEAKIESGTEIPYQEASSSGATSITFKKAVLGLTVTPNITPDGQIIMTVKINRDTPIDCTVDSLTTKCINTKHLNT
QAMVEDGGTLIVGGIYEEESTNAVNKVPILGDIPVVGNLFKSRGKRENRRELLIFITPRIMDNVGNNLRY

Nucleotide


Download         Length: 2133 bp        

>NTDB_id=449260 FOC66_RS06975 WP_003748961.1 1477763..1479895(-) (pilQ) [Neisseria mucosa strain FDAARGOS_758]
ATGAAAACCAAGCACATGACAAAATTATTTGCCGGCTTCAGCGTTGCCCTCGCTGTTCAGACGGCCTTTGCAGGCAATAT
TACCGATATCAACGTTTCCACTTTGCCTGACAACCAAAAAATCATCAAAATCCGTTTCGACAAAGACGTCACCACACCTC
ATGGTTTTGTAACATCTACTCCGGCGCGTATTGCATTGGATTTTGCCAATACCAATATCCGTTTGCCTCAGCCTGTTTTG
GAATATGCCGACCCATTGCTGCATCAAATTACTGCGGCGCAAAACAATGACCGCGCACGCGTGGTTTTGGGTTTGAACAA
AATCAGCCAATACAATACCGAAATTCGCGACAACGAAGTTTGGGTATTTGTAAACGAATCTACTGACCAAACCAATGCGG
CCGTTGCAAATGAACGTGCGGCTACGCCGTCTACCGCGCGTGCTGCTCAGACTTATCAAGCCGTTTCAGCAGCCAATATT
GATTTTCGCAAAGGCGCACGCAATTCCGGCATTATTGAATTGTCCGCCCCTGGTTTCAGCGGACAGCCGGACATTAAACA
GCAGCGTGACCGCGTCGTTGTAACCTTGAAAAACCATACGCTGCCGACACAAGCGCAACGCAGTTTGGATGTGGCTGACT
TCAATACGCCTGTACAAAACGTTACGCTCAAACGTATCGGCAATTCTACCCAGCTCATTATCCGCAACAATAATGCAAAT
TGGGACATCAATACCAAAGCTTCTTCCGGACGCTTTGTATTTGAAGTATCGCCTAAAGCCGCCAATACCGAATCCGGCGG
TTTGAACCAAAATGCAAACAAATCGTTCAAAGGCCGTAAAATTTCCTTGGACTTCCAAGATGTAGAAGTCCGTACCATTT
TGCAGATTTTGGCAAAAGAATCCGGCGTGAATATTGTTGCCAGCGATACCGTCAAAGGCACCATGACCCTGTCCCTGAAA
GAGGTACCTTGGGATCAGGCTTTGGACTTGGTCATGCAGGCGCGCAATTTGGATATGCGCCGTCAAGGCAACATCATCAA
TATCGCACCTCGCGATGAATTGTTGGCAAAAGACAAAGCCTTCTTGCAGGCGGAAAAAGAGATTGCCGAATTGGGTCCGC
TGTATTCTCAAACCTTCCAGTTGAAATACAAAAACGTGGAAGAATTCCGCAAAATTTTGCGTTTGGAAGAATACGACAGC
AATAATTCCAATACCCGCAACACTCTGTTGAGCAACCGAGGCAGCGCCTTAATCGATCCGGCCACCAATACGCTGATCGT
AACCGACAACCGCGGCGTGATTGAGAAATTCCGCAAACTGATTGATGAATTGGATGTTCCAACCCGTCAAGTAATGGTGG
AAGCGCGTATTGTGGAGGCAGAAGATACCTTCTTCCGCAACTTGGGCGTTAAATTCGGTTCCGGTGGTGCGAGCGGCCGT
ACGGCATGGGGTAGCAACTGGAGCAATGCGCAAGCCAACCATAACACCAATGCTTCGTTTAACCGTGGTGATGTCGGCTA
TCCTACTTGGTCCTTGGATCCAAACGTCAGCCTGCCGACCGCAGCCGCAGTCAACAGCATTGCGCTGGTGCGTGCGTTCT
CGTCTGGCGCATTGGGTTTGGAAATCAGCGCGTCTGAAGAGCAAGGTAAGAGCAAAACCATTTCCAATCCGCGCGTGCTG
ACACAAGACCGCAAAGAAGCCAAAATTGAATCCGGTACGGAAATTCCTTACCAAGAGGCTTCTTCCAGCGGTGCGACTTC
GATTACCTTCAAGAAAGCCGTTTTGGGCTTGACCGTAACGCCGAACATTACGCCTGACGGTCAAATCATCATGACTGTGA
AGATTAATCGTGATACCCCGATTGACTGTACCGTAGATTCTCTGACAACCAAGTGTATCAACACCAAACACTTGAATACC
CAAGCCATGGTTGAAGATGGAGGTACGCTGATTGTCGGTGGTATTTACGAGGAAGAAAGCACCAATGCGGTGAACAAAGT
ACCTATTTTGGGTGATATTCCTGTTGTCGGCAATTTGTTCAAATCACGCGGTAAACGTGAAAACCGCCGCGAGCTGTTGA
TCTTCATCACGCCGCGCATTATGGATAATGTGGGTAACAATCTGCGTTACTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(545-702)

AMIN domain (AMIN)

(38-117)

Bacterial type II/III secretion system short domain (Secretin_N)

(377-450)

Secretin and TonB N terminus short domain (STN)

(303-350)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

60.076

100

0.668
  pilQ Neisseria meningitidis M1080

60.691

100

0.668
  pilQ Neisseria gonorrhoeae strain FA1090

64.043

100

0.665