Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GGS_RS08025 Genome accession   NC_018712
Coordinates   1641971..1642612 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis RE378     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1636971..1647612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GGS_RS08005 (GGS_1517) - 1638346..1638984 (+) 639 WP_015017292.1 YigZ family protein -
  GGS_RS08010 (GGS_1518) cysK 1639088..1640023 (+) 936 WP_003062335.1 cysteine synthase A -
  GGS_RS08015 (GGS_1519) - 1640175..1640534 (-) 360 WP_015017293.1 S1 RNA-binding domain-containing protein -
  GGS_RS08020 (GGS_1520) - 1640534..1641934 (-) 1401 WP_042357970.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GGS_RS08025 (GGS_1521) vraR 1641971..1642612 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  GGS_RS08030 (GGS_1522) - 1642605..1643609 (-) 1005 WP_003061197.1 sensor histidine kinase -
  GGS_RS08035 (GGS_1523) liaF 1643606..1644250 (-) 645 WP_042358069.1 cell wall-active antibiotics response protein LiaF -
  GGS_RS08040 (GGS_1524) pknB 1644426..1646321 (-) 1896 WP_004230538.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GGS_RS08045 (GGS_1525) - 1646318..1647058 (-) 741 WP_014612505.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=44926 GGS_RS08025 WP_014612503.1 1641971..1642612(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=44926 GGS_RS08025 WP_014612503.1 1641971..1642612(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACTTCTTATTTGGACAATGAGAAAATTTATCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGATCAACACCCTGATTTGCATGAAGAGCTAACCGCGCGTGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTTAAAACGCATGTGTCTAATATTCT
TGCTAAGCTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376

Multiple sequence alignment